PI3K gamma-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling.
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Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13Targeting the B-cell receptor signaling pathway in B lymphoid malignanciesPI3Kγ Is Critical for Dendritic Cell-Mediated CD8+ T Cell Priming and Viral Clearance during Influenza Virus Infectionp110γ/δ Double-Deficiency Induces Eosinophilia and IgE Production but Protects from OVA-Induced Airway InflammationAnti-malarial drug artesunate attenuates experimental allergic asthma via inhibition of the phosphoinositide 3-kinase/Akt pathwayToll-like receptor-9 agonist inhibits airway inflammation, remodeling and hyperreactivity in mice exposed to chronic environmental tobacco smoke and allergenPhosphoinositide 3-kinase gamma regulates airway smooth muscle contraction by modulating calcium oscillations.Anti-Asthma Simplified Herbal Medicine Intervention-induced long-lasting tolerance to allergen exposure in an asthma model is interferon-γ, but not transforming growth factor-β dependentAdiponectin-deficient mice are protected against tobacco-induced inflammation and increased emphysemaPI3Kγ drives priming and survival of autoreactive CD4(+) T cells during experimental autoimmune encephalomyelitis.Aldose reductase inhibition prevents allergic airway remodeling through PI3K/AKT/GSK3β pathway in mice.Epinephrine Activation of the β2-Adrenoceptor Is Required for IL-13-Induced Mucin Production in Human Bronchial Epithelial Cells.A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsivenessTargeting phosphoinositide 3-kinase γ in airway smooth muscle cells to suppress interleukin-13-induced mouse airway hyperresponsiveness.The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic DiseasesExacerbation of allergic inflammation in mice exposed to diesel exhaust particles prior to viral infection.Environmental tobacco smoke exposure does not prevent corticosteroids reducing inflammation, remodeling, and airway hyperreactivity in mice exposed to allergen.Phosphatidylinositol 3-kinase isoforms as targets in respiratory disease.FIZZ1 promotes airway remodeling through the PI3K/Akt signaling pathway in asthmaThe roles and regulation of the actin cytoskeleton, intermediate filaments and microtubules in smooth muscle cell migration.Phosphoinositide 3-kinase p110γ in immunity.Role of phosphoinositide 3-kinase in the pathogenesis of acute pancreatitis.Mechanisms and treatments for severe, steroid-resistant allergic airway disease and asthma.Eosinophilic inflammation in allergic asthma.Phosphoinositide 3-Kinase in Asthma: Novel Roles and Therapeutic Approaches.Comprehensive attenuation of IL-25-induced airway hyperresponsiveness, inflammation and remodelling by the PI3K inhibitor LY294002.A phosphatidylinositol 3-kinase inhibitor strongly suppressed pulmonary vascular remodeling of allergic vasculitis in a murine model.
P2860
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P2860
PI3K gamma-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
PI3K gamma-deficient mice have ...... mmation and airway remodeling.
@en
PI3K gamma-deficient mice have ...... mmation and airway remodeling.
@nl
type
label
PI3K gamma-deficient mice have ...... mmation and airway remodeling.
@en
PI3K gamma-deficient mice have ...... mmation and airway remodeling.
@nl
prefLabel
PI3K gamma-deficient mice have ...... mmation and airway remodeling.
@en
PI3K gamma-deficient mice have ...... mmation and airway remodeling.
@nl
P2093
P2860
P1476
PI3K gamma-deficient mice have ...... mmation and airway remodeling.
@en
P2093
Dae Hyun Lim
Dae Jin Song
David H Broide
Jae Youn Cho
Marina Miller
Sang Yeub Lee
P2860
P304
P356
10.1152/AJPLUNG.90275.2008
P577
2008-11-21T00:00:00Z