Beta cell mass in diabetes: a realistic therapeutic target?
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Role of microRNAs in islet beta-cell compensation and failure during diabetesDiabetes in Danish bank voles (M. glareolus): survivorship, influence on weight, and evaluation of polydipsia as a screening tool for hyperglycaemiaAnti-diabetic Agents in Type 2 Diabetes: A Review of New Data Presented and Discussed on the EASD meeting in Rome, 2008.Successful β cells islet regeneration in streptozotocin-induced diabetic baboons using ultrasound-targeted microbubble gene therapy with cyclinD2/CDK4/GLP1.Beta-cell replication is increased in donor organs from young patients after prolonged life support.The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) siTherapeutic Approaches for Preserving or Restoring Pancreatic β-Cell Function and Mass.Characterisation of age-dependent beta cell dynamics in the male db/db mice.Beta Cell Mass Restoration in Alloxan-Diabetic Mice Treated with EGF and GastrinTransient overexpression of cyclin D2/CDK4/GLP1 genes induces proliferation and differentiation of adult pancreatic progenitors and mediates islet regenerationThe pancreatic beta cell surface proteome.The protective effect of peroxiredoxin II on oxidative stress induced apoptosis in pancreatic β-cellsThe hyperbolic effect of density and strength of inter beta-cell coupling on islet bursting: a theoretical investigation.Extreme obesity induces massive beta cell expansion in mice through self-renewal and does not alter the beta cell lineage.Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival.Phosphodiesterase 5 inhibition improves beta-cell function in metabolic syndrome.Exploring functional beta-cell heterogeneity in vivo using PSA-NCAM as a specific marker.Adaptive beta-cell proliferation is severely restricted with advanced age.Linking the genetics of type 2 diabetes with low birth weight: a role for prenatal islet maldevelopment?Functional assessment of pancreatic beta-cell area in humans.Impact of obesity severity and duration on pancreatic β- and α-cell dynamics in normoglycemic non-human primates.Inhibitor selectivity in the clinical application of dipeptidyl peptidase-4 inhibition.Treating type 2 diabetes: incretin mimetics and enhancers.PPAR-α Agonist Fenofibrate Reduces Insulin Resistance in Impaired Glucose Tolerance Patients with Hypertriglyceridemia: A Cross-Sectional Study.Incretin-based therapies--review of the physiology, pharmacology and emerging clinical experience.Possible role of GLP-1 and its agonists in the treatment of type 1 diabetes mellitus.Diabetes mellitus: Exploring the challenges in the drug development process.Do statins cause diabetes?Novel approaches to drug discovery for the treatment of type 2 diabetes.The treatment of type 1 diabetes mellitus with agents approved for type 2 diabetes mellitus.Pancreatic β-Cell production of CXCR3 ligands precedes diabetes onset.Synergistic activations of REG I α and REG I β promoters by IL-6 and Glucocorticoids through JAK/STAT pathway in human pancreatic β cells.Pancreatic Islet-Like Three-Dimensional Aggregates Derived From Human Embryonic Stem Cells Ameliorate Hyperglycemia in Streptozotocin-Induced Diabetic Mice.Islet Microencapsulation: Strategies and Clinical Status in Diabetes.[Xenogeneic cell therapeutics: Treatment of type 1 diabetes using porcine pancreatic islets and islet cells].The dynamic plasticity of insulin production in β-cells.Role of reduced β-cell mass versus impaired β-cell function in the pathogenesis of type 2 diabetes.Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes.Circulating microRNA-375 as biomarker of pancreatic beta cell death and protection of beta cell mass by cytoprotective compounds.Isolation of genes involved in pancreas regeneration by subtractive hybridization.
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Beta cell mass in diabetes: a realistic therapeutic target?
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 04 March 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Beta cell mass in diabetes: a realistic therapeutic target?
@en
Beta cell mass in diabetes: a realistic therapeutic target?
@nl
type
label
Beta cell mass in diabetes: a realistic therapeutic target?
@en
Beta cell mass in diabetes: a realistic therapeutic target?
@nl
prefLabel
Beta cell mass in diabetes: a realistic therapeutic target?
@en
Beta cell mass in diabetes: a realistic therapeutic target?
@nl
P2860
P1433
P1476
Beta cell mass in diabetes: a realistic therapeutic target?
@en
P2093
P2860
P2888
P304
P356
10.1007/S00125-008-0936-9
P577
2008-03-04T00:00:00Z