Cyclic AMP: master regulator of innate immune cell function.
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Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungsThe cAMP Pathway as Therapeutic Target in Autoimmune and Inflammatory DiseasesSelective Phosphodiesterase Inhibitors for Psoriasis: Focus on ApremilastEmerging roles for lysophosphatidylserine in resolution of inflammationA phosphodiesterase 4B-dependent interplay between tumor cells and the microenvironment regulates angiogenesis in B-cell lymphoma.Managing patients with psoriatic disease: the diagnosis and pharmacologic treatment of psoriatic arthritis in patients with psoriasisMolecular mechanisms underlying β-adrenergic receptor-mediated cross-talk between sympathetic neurons and immune cellsSuccessful shortening of tuberculosis treatment using adjuvant host-directed therapy with FDA-approved phosphodiesterase inhibitors in the mouse modelRole of the angiotensin II AT2 receptor in inflammation and oxidative stress: opposing effects in lean and obese Zucker ratsMaggot secretions skew monocyte-macrophage differentiation away from a pro-inflammatory to a pro-angiogenic typeKnockdown of lung phosphodiesterase 2A attenuates alveolar inflammation and protein leak in a two-hit mouse model of acute lung injury.Overview of community-acquired pneumonia and the role of inflammatory mechanisms in the immunopathogenesis of severe pneumococcal disease.Elevated cyclic AMP and PDE4 inhibition induce chemokine expression in human monocyte-derived macrophagesE-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infectionPhosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair.Transient increase in cyclic AMP localized to macrophage phagosomes.Human monocytes respond to extracellular cAMP through A2A and A2B adenosine receptorsCysteinyl leukotriene receptor-1 antagonists as modulators of innate immune cell functionThe anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approachesInduction of leptin resistance by activation of cAMP-Epac signaling.Ghrelin induces leptin resistance by activation of suppressor of cytokine signaling 3 expression in male rats: implications in satiety regulationActivation of cyclic adenosine monophosphate-dependent protein kinase a signaling prevents liver ischemia/reperfusion injury in micePhosphodiesterase 2A is a major negative regulator of iNOS expression in lipopolysaccharide-treated mouse alveolar macrophages.Epac1 and Epac2 are differentially involved in inflammatory and remodeling processes induced by cigarette smoke.Blocking of exchange proteins directly activated by cAMP leads to reduced replication of Middle East respiratory syndrome coronavirus.Targeting protein-protein interactions within the cyclic AMP signaling system as a therapeutic strategy for cardiovascular disease.Anti-inflammatory effects of secondary metabolites of marine Pseudomonas sp. in human neutrophils are through inhibiting P38 MAPK, JNK, and calcium pathways.Pituitary adenylate cyclase activating peptide deficient mice exhibit impaired thymic and extrathymic regulatory T cell proliferation during EAEDistinct protein kinase A anchoring proteins direct prostaglandin E2 modulation of Toll-like receptor signaling in alveolar macrophages.Inhibitory role of sphingosine 1-phosphate receptor 2 in macrophage recruitment during inflammation.Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor.Host targeted activity of pyrazinamide in Mycobacterium tuberculosis infectionPathogenomic inference of virulence-associated genes in Leptospira interrogans.Prostaglandin E2 and SOCS1 have a role in intestinal immune tolerance.Prostaglandin E2 induction during mouse adenovirus type 1 respiratory infection regulates inflammatory mediator generation but does not affect viral pathogenesis.Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetesProstaglandin E2 and the pathogenesis of pulmonary fibrosis.Proinflammatory cytokine regulation of cyclic AMP-phosphodiesterase 4 signaling in microglia in vitro and following CNS injury.Novel PDE4 inhibitors derived from Chinese medicine forsythia.Relaxin modulates proinflammatory cytokine secretion from human decidual macrophages
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Cyclic AMP: master regulator of innate immune cell function.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 March 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Cyclic AMP: master regulator of innate immune cell function.
@en
Cyclic AMP: master regulator of innate immune cell function.
@nl
type
label
Cyclic AMP: master regulator of innate immune cell function.
@en
Cyclic AMP: master regulator of innate immune cell function.
@nl
prefLabel
Cyclic AMP: master regulator of innate immune cell function.
@en
Cyclic AMP: master regulator of innate immune cell function.
@nl
P2860
P50
P356
P1476
Cyclic AMP: master regulator of innate immune cell function
@en
P2860
P304
P356
10.1165/RCMB.2008-0091TR
P577
2008-03-06T00:00:00Z