Fundus autofluorescence in the Abca4(-/-) mouse model of Stargardt disease--correlation with accumulation of A2E, retinal function, and histology. - Wikidata - awgldk - TriplyDB

Fundus autofluorescence in the Abca4(-/-) mouse model of Stargardt disease--correlation with accumulation of A2E, retinal function, and histology.

Fundus autofluorescence in the Abca4(-/-) mouse model of Stargardt disease--correlation with accumulation of A2E, retinal function, and histology.

http://www.wikidata.org/entity/Q37105977

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Stargardt disease: clinical features, molecular genetics, animal models and therapeutic options Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease Correlation between SD-OCT, immunocytochemistry and functional findings in an animal model of retinal degeneration.Endophenotypes for Age-Related Macular Degeneration: Extending Our Reach into the Preclinical Stages of Disease.Protein misfolding and the pathogenesis of ABCA4-associated retinal degenerations.Quantitative Fundus Autofluorescence and Optical Coherence Tomography in ABCA4 Carriers.Rescue of the Stargardt phenotype in Abca4 knockout mice through inhibition of vitamin A dimerization.Predicting Progression of ABCA4-Associated Retinal Degenerations Based on Longitudinal Measurements of the Leading Disease Front.The adult zebrafish retina: In vivo optical sectioning with Confocal Scanning Laser Ophthalmoscopy and Spectral-Domain Optical Coherence Tomography.Protective responses to sublytic complement in the retinal pigment epithelium Single residue AAV capsid mutation improves transduction of photoreceptors in the Abca4-/- mouse and bipolar cells in the rd1 mouse and human retina ex vivo.Monoallelic ABCA4 Mutations Appear Insufficient to Cause Retinopathy: A Quantitative Autofluorescence Study Multiple A2E treatments lead to melanization of rod outer segment-challenged ARPE-19 cells.Inclusion of the Woodchuck Hepatitis Virus Posttranscriptional Regulatory Element Enhances AAV2-Driven Transduction of Mouse and Human Retina Towards Treatment of Stargardt Disease: Workshop Organized and Sponsored by the Foundation Fighting Blindness.A2E and lipofuscin distributions in macaque retinal pigment epithelium are similar to human.Localization and functional characterization of the p.Asn965Ser (N965S) ABCA4 variant in mice reveal pathogenic mechanisms underlying Stargardt macular degeneration.Mutations in GPR143/OA1 and ABCA4 Inform Interpretations of Short-Wavelength and Near-Infrared Fundus Autofluorescence.The P2Y12 Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4-/- Mouse Model of Retinal Degeneration.

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Fundus autofluorescence in the Abca4(-/-) mouse model of Stargardt disease--correlation with accumulation of A2E, retinal function, and histology.

http://www.wikidata.org/entity/Q37105977

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scientific article published on 19 August 2013

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vedecký článok

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Fundus autofluorescence in the ...... tinal function, and histology.

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Fundus autofluorescence in the ...... tinal function, and histology.

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Fundus autofluorescence in the ...... tinal function, and histology.

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Fundus autofluorescence in the ...... tinal function, and histology.

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Investigative Ophthalmology & Visual Science

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Fundus autofluorescence in the ...... tinal function, and histology.

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Alun R Barnard

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Emma Carter

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Mandeep S Singh

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Peter Charbel Issa

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Robert E MacLaren

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Roxana A Radu

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Ulrich Schraermeyer

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Zhichun Jiang

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P2860

A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy

Correction of the disease phenotype in the mouse model of Stargardt disease by lentiviral gene therapy

Retinitis pigmentosa caused by a homozygous mutation in the Stargardt disease gene ABCR

Insights into the function of Rim protein in photoreceptors and etiology of Stargardt's disease from the phenotype in abcr knockout mice

Mutation of the Stargardt disease gene (ABCR) in age-related macular degeneration

Autosomal recessive retinitis pigmentosa and cone-rod dystrophy caused by splice site mutations in the Stargardt's disease gene ABCR

Reductions in Serum Vitamin A Arrest Accumulation of Toxic Retinal Fluorophores: A Potential Therapy for Treatment of Lipofuscin-Based Retinal Diseases

Cone photoreceptor abnormalities correlate with vision loss in patients with Stargardt disease.

Oxidation causes melanin fluorescence.

Fundus autofluorescence in Stargardt macular dystrophy-fundus flavimaculatus.

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5602-5612

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10.1167/IOVS.13-11688

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2013-08-19T00:00:00Z

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3747716

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