Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling
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Role of Nrf2 in oxidative stress and toxicityN-acetylcysteine in COPD: why, how, and when?Concerted action of Nrf2-ARE pathway, MRN complex, HMGB1 and inflammatory cytokines - implication in modification of radiation damagep62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogrammingWhen NRF2 talks, who's listening?CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2Aging and immune function: molecular mechanisms to interventionsMechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative diseasemiR-125b transcriptionally increased by Nrf2 inhibits AhR repressor, which protects kidney from cisplatin-induced injuryKeap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals.The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblastsNuclear factor (erythroid-derived 2)-like 2 regulates drug resistance in pancreatic cancer cells.Genetic deletion of Nrf2 promotes immortalization and decreases life span of murine embryonic fibroblasts.Disruption of Nrf2 impairs the resolution of hyperoxia-induced acute lung injury and inflammation in miceInnate immunity against bacterial infection following hyperoxia exposure is impaired in NRF2-deficient mice.The toxic effects and possible mechanisms of Brusatol on mouse oocytesReview article: the role of oxidative stress in pathogenesis and treatment of inflammatory bowel diseases.PERK promotes cancer cell proliferation and tumor growth by limiting oxidative DNA damageGlobal mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis.Comparative analysis of organophosphate degrading enzymes from diverse species.DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs.Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo.PI3K-AKT Signaling via Nrf2 Protects against Hyperoxia-Induced Acute Lung Injury, but Promotes Inflammation Post-Injury Independent of Nrf2 in MiceConditional deletion of Nrf2 in airway epithelium exacerbates acute lung injury and impairs the resolution of inflammation.Transforming growth factor-β and nuclear factor E2–related factor 2 regulate antioxidant responses in airway smooth muscle cells: role in asthma.Nrf2 links epidermal barrier function with antioxidant defenseCrosstalk between Nrf2 and Notch signaling.UHRF1 regulation of the Keap1-Nrf2 pathway in pancreatic cancer contributes to oncogenesisN-acetylcysteine protects murine alveolar type II cells from cigarette smoke injury in a nuclear erythroid 2-related factor-2-independent mannerIron-mediated retinal degeneration in haemojuvelin-knockout mice.Absence of iron-regulatory protein Hfe results in hyperproliferation of retinal pigment epithelium: role of cystine/glutamate exchangerA nuclear glutathione cycle within the cell cycle.The cytoprotective role of the Keap1-Nrf2 pathway.Preexposure to Olive Oil Polyphenols Extract Increases Oxidative Load and Improves Liver Mass Restoration after Hepatectomy in Mice via Stress-Sensitive Genes.Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosisPaternal smoking and germ cell death: A mechanistic link to the effects of cigarette smoke on spermatogenesis and possible long-term sequelae in offspring.MiRNAs-mediated cisplatin resistance in breast cancer.Cigarette smoke-induced cell cycle arrest in spermatocytes [GC-2spd(ts)] is mediated through crosstalk between Ahr-Nrf2 pathway and MAPK signaling.Neurodegeneration and the Brain Tumor Microenvironment. [corrected]Conditioned Media Downregulates Nuclear Expression of Nrf2.
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Genetic disruption of the Nrf2 compromises cell-cycle progression by impairing GSH-induced redox signaling
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 09 June 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Genetic disruption of the Nrf2 ...... ng GSH-induced redox signaling
@en
Genetic disruption of the Nrf2 ...... g GSH-induced redox signaling.
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type
label
Genetic disruption of the Nrf2 ...... ng GSH-induced redox signaling
@en
Genetic disruption of the Nrf2 ...... g GSH-induced redox signaling.
@nl
prefLabel
Genetic disruption of the Nrf2 ...... ng GSH-induced redox signaling
@en
Genetic disruption of the Nrf2 ...... g GSH-induced redox signaling.
@nl
P2093
P2860
P356
P1433
P1476
Genetic disruption of the Nrf2 ...... ng GSH-induced redox signaling
@en
P2093
M Yamamoto
P G Fallon
S R Kleeberger
T W Kensler
P2860
P2888
P304
P356
10.1038/ONC.2008.188
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P50
P577
2008-06-09T00:00:00Z