The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
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Membrane-anchored uPAR regulates the proliferation, marrow pool size, engraftment, and mobilization of mouse hematopoietic stem/progenitor cells.Plasminogen regulates cardiac repair after myocardial infarction through its noncanonical function in stem cell homing to the infarcted heart.Tissue type plasminogen activator regulates myeloid-cell dependent neoangiogenesis during tissue regeneration.Rapid mobilization of hematopoietic progenitors by AMD3100 and catecholamines is mediated by CXCR4-dependent SDF-1 release from bone marrow stromal cells.Protective effect of the Japanese traditional medicine juzentaihoto on myelosuppression induced by the anticancer drug TS-1 and identification of a potential biomarker of this effect.MMP9 is protective against lethal inflammatory mass lesions in the mouse colon.Gender affects skin wound healing in plasminogen deficient mice.PAI-1 antagonists: the promise and the peril.Plasminogen regulates stromal cell-derived factor-1/CXCR4-mediated hematopoietic stem cell mobilization by activation of matrix metalloproteinase-9.Markers of coagulation activation and acute kidney injury in patients after hematopoietic cell transplantation.Systems analysis of gene ontology and biological pathways involved in post-myocardial infarction responses.Challenges for heart disease stem cell therapy.Plasmin therapy enhances mobilization of HPCs after G-CSFContribution of the fibrinolytic pathway to hematopoietic regeneration.Natural and engineered plasmin inhibitors: applications and design strategies.New functions of the fibrinolytic system in bone marrow cell-derived angiogenesis.Cell surface remodeling by plasmin: a new function for an old enzyme.The plasminogen system in regulating stem cell mobilization.Role of mesenchymal stem cell-derived fibrinolytic factor in tissue regeneration and cancer progression.Inhibition of plasmin attenuates murine acute graft-versus-host disease mortality by suppressing the matrix metalloproteinase-9-dependent inflammatory cytokine storm and effector cell trafficking.Hemostasis keeps the stem cell niche in order.Fibrinolysis-independent role of plasmin and its activators in the haematopoietic recovery after myeloablation.Early thrombin generation and impaired fibrinolysis after SCT associate with acute GVHD.Morphology and quantitative composition of hematopoietic cells in murine bone marrow and spleen of healthy subjects.Plasmin inhibitor reduces T-cell lymphoid tumor growth by suppressing matrix metalloproteinase-9-dependent CD11b(+)/F4/80(+) myeloid cell recruitment.TGF-β-induced intracellular PAI-1 is responsible for retaining hematopoietic stem cells in the niche.Leucocyte and Platelet-rich Fibrin: a carrier of autologous multipotent cells for regenerative medicine.Adipose Tissue-Derived Plasminogen Activator Inhibitor-1 Function and Regulation.Latexin regulates the abundance of multiple cellular proteins in hematopoietic stem cells.Inhibition of plasminogen activator inhibitor type-1 activity enhances rapid and sustainable hematopoietic regeneration.Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile.Roles of plasminogen in the alterations in bone marrow hematopoietic stem cells during bone repair.
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The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
@en
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
@nl
type
label
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
@en
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
@nl
prefLabel
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
@en
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
@nl
P2093
P2860
P1433
P1476
The plasminogen fibrinolytic pathway is required for hematopoietic regeneration.
@en
P2093
Beate Heissig
Haruyo Akiyama
Hideoki Ogawa
Hiromitsu Nakauchi
John Rømer
Ko Okumura
Koichi Hattori
Leif R Lund
Makiko Ohki
P2860
P304
P356
10.1016/J.STEM.2007.10.012
P407
P50
P577
2007-12-01T00:00:00Z