Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells. - Wikidata - awgldk - TriplyDB

Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

http://www.wikidata.org/entity/Q37106760

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A role of Miz-1 in Gfi-1-mediated transcriptional repression of CDKN1A Recent advances in understanding the molecular mechanisms of the development and function of Th17 cells TGF-β: guardian of T cell function Histone Posttranslational Modifications of CD4⁺ T Cell in Autoimmune Diseases Genome-wide analyses of transcription factor GATA3-mediated gene regulation in distinct T cell types Neutrophils in a mouse model of autoantibody-mediated arthritis: critical producers of Fc receptor gamma, the receptor for C5a, and lymphocyte function-associated antigen 1 Differentiation of effector CD4 T cell populations (*)Regulatory T cells: mechanisms of differentiation and function IL-4 attenuates Th1-associated chemokine expression and Th1 trafficking to inflamed tissues and limits pathogen clearance.TGF-β activation and function in immunity.Regulation of the T helper cell type 2 (Th2)/T regulatory cell (Treg) balance by IL-4 and STAT6 IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?Expression of 3G11 epitope defines subpopulations of regulatory T cells with different suppressive potency Complex interactions of transcription factors in mediating cytokine biology in T cells.Peripheral CD4+ T-cell differentiation regulated by networks of cytokines and transcription factors.Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells.Control of regulatory T cell lineage commitment and maintenance.Progesterone promotes differentiation of human cord blood fetal T cells into T regulatory cells but suppresses their differentiation into Th17 cells.T cell factor-1 negatively regulates expression of IL-17 family of cytokines and protects mice from experimental autoimmune encephalomyelitis.Krüppel-like factor 4 (KLF4) directly regulates proliferation in thymocyte development and IL-17 expression during Th17 differentiation.MicroRNA-31 negatively regulates peripherally derived regulatory T-cell generation by repressing retinoic acid-inducible protein 3.T helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production.Transcriptional regulatory networks for CD4 T cell differentiation.The Transcriptional Repressor Gfi1 Plays a Critical Role in the Development of NKT1- and NKT2-Type iNKT Cells Early intervention with gene-modified mesenchymal stem cells overexpressing interleukin-4 enhances anti-inflammatory responses and functional recovery in experimental autoimmune demyelination.Transcriptional regulation of Th2 cell differentiation.Heterogeneity and plasticity of T helper cells.T cell receptor/CARMA1/NF-κB signaling controls T-helper (Th) 17 differentiation How are T(H)2-type immune responses initiated and amplified?Neutrophils orchestrate their own recruitment in murine arthritis through C5aR and FcγR signaling.Nuclear orphan receptor NR2F6 directly antagonizes NFAT and RORγt binding to the Il17a promoter.It is time to beelieve the CD1a hype!Involvement of p300/CBP and epigenetic histone acetylation in TGF-β1-mediated gene transcription in mesangial cells Plasticity within the αβ⁺CD4⁺ T-cell lineage: when, how and what for?Arginase-1-dependent promotion of TH17 differentiation and disease progression by MDSCs in systemic lupus erythematosus.Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells.TGF-β cytokine signaling promotes CD8+ T cell development and low-affinity CD4+ T cell homeostasis by regulation of interleukin-7 receptor α expression.Translational mini-review series on Th17 cells: development of mouse and human T helper 17 cells.What determines Th2 differentiation, in vitro and in vivo?The Lysine Methyltransferase G9a in Immune Cell Differentiation and Function.

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Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

http://www.wikidata.org/entity/Q37106760

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 02 February 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

@da

vědecký článek

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name

Down-regulation of Gfi-1 expre ...... inducible regulatory T cells.

@en

Down-regulation of Gfi-1 expre ...... inducible regulatory T cells.

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type

label

Down-regulation of Gfi-1 expre ...... inducible regulatory T cells.

@en

Down-regulation of Gfi-1 expre ...... inducible regulatory T cells.

@nl

prefLabel

Down-regulation of Gfi-1 expre ...... inducible regulatory T cells.

@en

Down-regulation of Gfi-1 expre ...... inducible regulatory T cells.

@nl

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Journal of Experimental Medicine

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Down-regulation of Gfi-1 expre ...... + inducible regulatory T cells

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Dragana Jankovic

http://www.w3.org/2001/XMLSchema#string

Dustin E Schones

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Ethan M Shevach

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Gang Wei

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Kairong Cui

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Keji Zhao

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Liying Guo

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Todd S Davidson

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William E Paul

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P2860

A novel transcription factor, T-bet, directs Th1 lineage commitment

TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein

Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

Control of regulatory T cell development by the transcription factor Foxp3

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

High-resolution profiling of histone methylations in the human genome

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329-341

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scholarly article

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10.1084/JEM.20081666

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2

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206

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2009-02-02T00:00:00Z

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23972589

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19188499

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2646571

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