Differential effect of regional drug pressure on dihydrofolate reductase and dihydropteroate synthetase mutations in southern Mozambique.
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Crystallographic analysis reveals a novel second binding site for trimethoprim in active site double mutants of human dihydrofolate reductaseDeclining trend of Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant alleles after the withdrawal of Sulfadoxine-Pyrimethamine in North Western EthiopiaFive years of antimalarial resistance marker surveillance in Gaza Province, Mozambique, following artemisinin-based combination therapy roll outMarkers of anti-malarial drug resistance in Plasmodium falciparum isolates from Swaziland: identification of pfmdr1-86F in natural parasite isolatesFive years of large-scale dhfr and dhps mutation surveillance following the phased implementation of artesunate plus sulfadoxine-pyrimethamine in Maputo Province, Southern Mozambique.Anti-folate drug resistance in Africa: meta-analysis of reported dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant genotype frequencies in African Plasmodium falciparum parasite populations.Drug resistance maps to guide intermittent preventive treatment of malaria in African infants.Evolutionary biology and the avoidance of antimicrobial resistance.Optimum population-level use of artemisinin combination therapies: a modelling study.Rapid increase of Plasmodium falciparum dhfr/dhps resistant haplotypes, after the adoption of sulphadoxine-pyrimethamine as first line treatment in 2002, in southern Mozambique.Efficacy of sulphadoxine-pyrimethamine with or without artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in southern Mozambique: a randomized controlled trialMonitoring antifolate resistance in intermittent preventive therapy for malaria.Emerging implications of policies on malaria treatment: genetic changes in the gene affecting susceptibility to artemether-lumefantrine and artesunate-amodiaquine in Africa
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P2860
Differential effect of regional drug pressure on dihydrofolate reductase and dihydropteroate synthetase mutations in southern Mozambique.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Differential effect of regiona ...... ations in southern Mozambique.
@en
Differential effect of regiona ...... ations in southern Mozambique.
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type
label
Differential effect of regiona ...... ations in southern Mozambique.
@en
Differential effect of regiona ...... ations in southern Mozambique.
@nl
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Differential effect of regiona ...... ations in southern Mozambique.
@en
Differential effect of regiona ...... ations in southern Mozambique.
@nl
P2093
P2860
P1476
Differential effect of regiona ...... tations in southern Mozambique
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P2093
Brian Sharp
Cally Roper
Elizabeth Streat
Immo Kleinschmidt
Jaishree Raman
P2860
P304
P356
10.4269/AJTMH.2008.78.256
P407
P50
P577
2008-02-01T00:00:00Z