Canonical initiation factor requirements of the Myc family of internal ribosome entry segments. - Wikidata - awgldk - TriplyDB

Canonical initiation factor requirements of the Myc family of internal ribosome entry segments.

Canonical initiation factor requirements of the Myc family of internal ribosome entry segments.

http://www.wikidata.org/entity/Q37110582

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A Burkholderia pseudomallei toxin inhibits helicase activity of translation factor eIF4A The hnRNA-binding proteins hnRNP L and PTB are required for efficient translation of the Cat-1 arginine/lysine transporter mRNA during amino acid starvation Mining Functional Elements in Messenger RNAs: Overview, Challenges, and Perspectives eIF4A inhibition allows translational regulation of mRNAs encoding proteins involved in Alzheimer's disease Upstream ORF affects MYCN translation depending on exon 1b alternative splicing Toward a structural understanding of IRES RNA function Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1.Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states.Quantitative profiling of in vivo-assembled RNA-protein complexes using a novel integrated proteomic approach An internal ribosome entry site in the 5' untranslated region of epidermal growth factor receptor allows hypoxic expression Equol, an isoflavone metabolite, regulates cancer cell viability and protein synthesis initiation via c-Myc and eIF4G.Expression of truncated eukaryotic initiation factor 3e (eIF3e) resulting from integration of mouse mammary tumor virus (MMTV) causes a shift from cap-dependent to cap-independent translation.Functional and structural analysis of maize hsp101 IRES.DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation The soy isoflavone equol may increase cancer malignancy via up-regulation of eukaryotic protein synthesis initiation factor eIF4G The insulin receptor cellular IRES confers resistance to eIF4A inhibition.RNA structure: new messages in translation, replication and disease. Workshop on the role of RNA structures in the translation of viral and cellular RNAs.RNA-binding proteins impacting on internal initiation of translation.Remodelling of a polypyrimidine tract-binding protein complex during apoptosis activates cellular IRESs Role of Eukaryotic Initiation Factors during Cellular Stress and Cancer Progression The biological and therapeutic relevance of mRNA translation in cancer.Translational regulation of the cell cycle: when, where, how and why?RNA binding protein/RNA element interactions and the control of translation KSR1 and EPHB4 Regulate Myc and PGC1β To Promote Survival of Human Colon Tumors.Hippuristanol - A potent steroid inhibitor of eukaryotic initiation factor 4A.Targeting Translation Initiation Bypasses Signaling Crosstalk Mechanisms That Maintain High MYC Levels in Colorectal Cancer.Requirement of rRNA methylation for 80S ribosome assembly on a cohort of cellular internal ribosome entry sites.Multiple isoforms of the translation initiation factor eIF4GII are generated via use of alternative promoters, splice sites and a non-canonical initiation codon.Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1.An accurately preorganized IRES RNA structure enables eIF4G capture for initiation of viral translation.TRAP1-dependent regulation of p70S6K is involved in the attenuation of protein synthesis and cell migration: relevance in human colorectal tumors The chaperonin CCT interacts with and mediates the correct folding and activity of three subunits of translation initiation factor eIF3: b, i and h.Targeting RNA helicases in cancer: The translation trap.Translation acrobatics: how cancer cells exploit alternate modes of translational initiation

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Canonical initiation factor requirements of the Myc family of internal ribosome entry segments.

http://www.wikidata.org/entity/Q37110582

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 05 January 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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Canonical initiation factor re ...... ernal ribosome entry segments.

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Molecular and Cellular Biology

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Canonical initiation factor re ...... ernal ribosome entry segments.

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Anne E Willis

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Keith A Spriggs

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Laura C Cobbold

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Lindsay A Wilson

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Mark J Coldwell

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Mark Stoneley

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Martin Bushell

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Rebecca E Cooper

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Simon J Morley

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Ya-Ching Shen

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P2860

Rotavirus RNA-binding protein NSP3 interacts with eIF4GI and evicts the poly(A) binding protein from eIF4F.

L-Myc protein synthesis is initiated by internal ribosome entry.

Physical association of eukaryotic initiation factor 4G (eIF4G) with eIF4A strongly enhances binding of eIF4G to the internal ribosomal entry site of encephalomyocarditis virus and is required for internal initiation of translation

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Specific interaction of eukaryotic translation initiation factor 3 with the 5' nontranslated regions of hepatitis C virus and classical swine fever virus RNAs.

Initiation factor-independent translation mediated by the hepatitis C virus internal ribosome entry site

Crystal structure of an RNA tertiary domain essential to HCV IRES-mediated translation initiation

A conserved RNA structure within the HCV IRES eIF3-binding site

Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure

The Apaf-1 internal ribosome entry segment attains the correct structural conformation for function via interactions with PTB and unr

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1565-1574

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scholarly article

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10.1128/MCB.01283-08

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6

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29

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Catherine L Jopling

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2009-01-05T00:00:00Z

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19124605

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2648239

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