A network of hydrophobic residues impeding helix alphaC rotation maintains latency of kinase Gcn2, which phosphorylates the alpha subunit of translation initiation factor 2.

A network of hydrophobic residues impeding helix alphaC rotation maintains latency of kinase Gcn2, which phosphorylates the alpha subunit of translation initiation factor 2.

Item
http://www.wikidata.org/entity/Q37110590
Genome-wide analysis of tRNA charging and activation of the eIF2 kinase Gcn2pEvidence that eukaryotic translation elongation factor 1A (eEF1A) binds the Gcn2 protein C terminus and inhibits Gcn2 activityPhosphorylation of initiation factor eIF2 in response to stress conditions is mediated by acidic ribosomal P1/P2 proteins in Saccharomyces cerevisiae.Enhanced interaction between pseudokinase and kinase domains in Gcn2 stimulates eIF2α phosphorylation in starved cellsSnf1 promotes phosphorylation of the alpha subunit of eukaryotic translation initiation factor 2 by activating Gcn2 and inhibiting phosphatases Glc7 and Sit4.Interaction between the tRNA-binding and C-terminal domains of Yeast Gcn2 regulates kinase activity in vivo.Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism.Mechanism and Regulation of Protein Synthesis in Saccharomyces cerevisiae.Auto-phosphorylation Represses Protein Kinase R Activity.Integrated Stress Responses to Bacterial Pathogenesis Patterns.
P2860

A network of hydrophobic residues impeding helix alphaC rotation maintains latency of kinase Gcn2, which phosphorylates the alpha subunit of translation initiation factor 2.

Item
http://www.wikidata.org/entity/Q37110590
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 29 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A network of hydrophobic resid ...... anslation initiation factor 2.
@en
A network of hydrophobic resid ...... anslation initiation factor 2.
@nl
type
label
A network of hydrophobic resid ...... anslation initiation factor 2.
@en
A network of hydrophobic resid ...... anslation initiation factor 2.
@nl
prefLabel
A network of hydrophobic resid ...... anslation initiation factor 2.
@en
A network of hydrophobic resid ...... anslation initiation factor 2.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932
P356
P1433
P1476
A network of hydrophobic resid ...... ranslation initiation factor 2
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P921
P932