Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer.
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The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutationsThe clinical and functional significance of c-Met in breast cancer: a reviewDevelopment of c-MET pathway inhibitors.Multiple regulatory mechanisms of hepatocyte growth factor expression in malignant cells with a short poly(dA) sequence in the HGF gene promoter.Genomic instability causes HGF gene activation in colon cancer cells, promoting their resistance to necroptosis.Association between Hepatocyte Growth Factor (HGF) Gene Polymorphisms and Serum HGF Levels in Patients with Rheumatoid Arthritis.Signaling network state predicts twist-mediated effects on breast cell migration across diverse growth factor contexts.The HGF inhibitory peptide HGP-1 displays promising in vitro and in vivo efficacy for targeted cancer therapy.Effects of HGF gene polymorphisms and protein expression on transhepatic arterial chemotherapeutic embolism efficacy and prognosis in patients with primary liver cancer.Role of HGF in epithelial-stromal cell interactions during progression from benign breast disease to ductal carcinoma in situ.MET: a promising anticancer therapeutic target.Targeting the MET pathway for potential treatment of NSCLC.Preclinical and clinical evaluation of MET functions in cancer cells and in the tumor stroma.Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor Microenvironment.Identification of the source of elevated hepatocyte growth factor levels in multiple myeloma patientsHGF-MET cascade, a key target for inhibiting cancer metastasis: the impact of NK4 discovery on cancer biology and therapeutics.Functional Mechanisms of Microsatellite DNA in Eukaryotic Genomes.Overexpression of MACC1 leads to downstream activation of HGF/MET and potentiates metastasis and recurrence of colorectal cancer.Hepatocyte Growth Factor Isoforms in Tissue Repair, Cancer, and Fibrotic Remodeling.MET signaling in keratinocytes activates EGFR and initiates squamous carcinogenesis.
P2860
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P2860
Somatic mutation and functional polymorphism of a novel regulatory element in the HGF gene promoter causes its aberrant expression in human breast cancer.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 02 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Somatic mutation and functiona ...... ession in human breast cancer.
@en
Somatic mutation and functiona ...... ession in human breast cancer.
@nl
type
label
Somatic mutation and functiona ...... ession in human breast cancer.
@en
Somatic mutation and functiona ...... ession in human breast cancer.
@nl
prefLabel
Somatic mutation and functiona ...... ession in human breast cancer.
@en
Somatic mutation and functiona ...... ession in human breast cancer.
@nl
P2093
P2860
P356
P1476
Somatic mutation and functiona ...... ession in human breast cancer.
@en
P2093
Carla Johnson
Chunbin Zou
Marie C DeFrances
Reza Zarnegar
Robert Ferrell
P2860
P304
P356
10.1172/JCI36640
P407
P577
2009-02-02T00:00:00Z