CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth. - Wikidata - awgldk - TriplyDB

CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth.

CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth.

http://www.wikidata.org/entity/Q37117592

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CXCL14 as an emerging immune and inflammatory modulator The integrative roles of chemokines at the maternal-fetal interface in early pregnancy Tumor stroma as targets for cancer therapy Inhibition of tumor cell proliferation and motility by fibroblasts is both contact and soluble factor dependent.Differences in the nemosis response of normal and cancer-associated fibroblasts from patients with oral squamous cell carcinoma IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway Ionizing radiation abrogates the pro-tumorigenic capacity of cancer-associated fibroblasts co-implanted in xenografts.Gene expression profiling of cholangiocarcinoma-derived fibroblast reveals alterations related to tumor progression and indicates periostin as a poor prognostic marker.Distinctive responsiveness to stromal signaling accompanies histologic grade programming of cancer cells Fibroblast heterogeneity in the cancer wound.Leptin mediates tumor-stromal interactions that promote the invasive growth of breast cancer cells Macrophage Infiltration in Tumor Stroma is Related to Tumor Cell Expression of CD163 in Colorectal Cancer.p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner.A systems genetics approach identifies CXCL14, ITGAX, and LPCAT2 as novel aggressive prostate cancer susceptibility genes.Biological characteristics and genetic heterogeneity between carcinoma-associated fibroblasts and their paired normal fibroblasts in human breast cancer Effect of chronic restraint stress on human colorectal carcinoma growth in mice.FSP1+ fibroblasts promote skin carcinogenesis by maintaining MCP-1-mediated macrophage infiltration and chronic inflammation.Effect of acute exercise on prostate cancer cell growth Suppressed rate of carcinogenesis and decreases in tumour volume and lung metastasis in CXCL14/BRAK transgenic mice.Impaired Cell Cycle Regulation in a Natural Equine Model of Asthma.Transcriptional profiles of pilocytic astrocytoma are related to their three different locations, but not to radiological tumor features.Identification of stromally expressed molecules in the prostate by tag-profiling of cancer-associated fibroblasts, normal fibroblasts and fetal prostate Fibroblasts--a key host cell type in tumor initiation, progression, and metastasis.Carcinoma-Associated Fibroblasts Lead the Invasion of Salivary Gland Adenoid Cystic Carcinoma Cells by Creating an Invasive Track.Multifaceted tumor stromal fibroblasts Infiltrating bone marrow mesenchymal stem cells (BM-MSCs) increase prostate cancer cell invasion via altering the CCL5/HIF2α/androgen receptor signals.Chemokine CXCL14 is associated with prognosis in patients with colorectal carcinoma after curative resection.Metabolic reprogramming and inflammation act in concert to control vascular remodeling in hypoxic pulmonary hypertension.Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth.Fibroblasts as architects of cancer pathogenesis Smoking-induced CXCL14 expression in the human airway epithelium links chronic obstructive pulmonary disease to lung cancer Cross-species functional analysis of cancer-associated fibroblasts identifies a critical role for CLCF1 and IL-6 in non-small cell lung cancer in vivo.Spatiotemporal expression and functional implication of CXCL14 in the developing mice cerebellum.Hepatic carcinoma-associated fibroblasts induce IDO-producing regulatory dendritic cells through IL-6-mediated STAT3 activation.Carcinoma-associated fibroblasts are a rate-limiting determinant for tumour progression.Stromal fibroblasts present in breast carcinomas promote tumor growth and angiogenesis through adrenomedullin secretion A Crucial Role of CXCL14 for Promoting Regulatory T Cells Activation in Stroke Cancer associated fibroblasts: the dark side of the coin.The tumor microenvironment: part 1.Targeting the tumor microenvironment by immunotherapy: part 2.

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CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth.

http://www.wikidata.org/entity/Q37117592

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

@tr

scientific article published on 13 February 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

CXCL14 is an autocrine growth ...... ator of prostate tumor growth.

@en

CXCL14 is an autocrine growth ...... ator of prostate tumor growth.

@nl

type

label

CXCL14 is an autocrine growth ...... ator of prostate tumor growth.

@en

CXCL14 is an autocrine growth ...... ator of prostate tumor growth.

@nl

prefLabel

CXCL14 is an autocrine growth ...... ator of prostate tumor growth.

@en

CXCL14 is an autocrine growth ...... ator of prostate tumor growth.

@nl

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PNAS.0813144106

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Proceedings of the National Academy of Sciences of the United States of America

P1476

CXCL14 is an autocrine growth ...... ator of prostate tumor growth.

@en

P2093

Ake Borg

http://www.w3.org/2001/XMLSchema#string

Arne Ostman

http://www.w3.org/2001/XMLSchema#string

Christina Hägglöf

http://www.w3.org/2001/XMLSchema#string

Claudia Stolz

http://www.w3.org/2001/XMLSchema#string

Eleonor Olsson

http://www.w3.org/2001/XMLSchema#string

Lars Egevad

http://www.w3.org/2001/XMLSchema#string

Martin Augsten

http://www.w3.org/2001/XMLSchema#string

Mitchell J Frederick

http://www.w3.org/2001/XMLSchema#string

Panagiotis Tsagozis

http://www.w3.org/2001/XMLSchema#string

Patrick Micke

http://www.w3.org/2001/XMLSchema#string

P2860

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes

Cancer and the chemokine network

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

Molecular characterization of the tumor microenvironment in breast cancer.

Modulation of CXCL14 (BRAK) expression in prostate cancer.

Dancing to the tune of chemokines.

BRAK/CXCL14 is a potent inhibitor of angiogenesis and a chemotactic factor for immature dendritic cells.

Chemokines in tumor angiogenesis and metastasis

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3414-3419

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scholarly article

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10.1073/PNAS.0813144106

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9

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106

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2009-02-13T00:00:00Z

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24011678

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19218429

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2651265

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