Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture
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Planar cell polarity in the mammalian eye lensWNT/β-Catenin Signaling in Vertebrate Eye DevelopmentEfficient generation of lens progenitor cells from cataract patient-specific induced pluripotent stem cellsLoss of Dlg-1 in the mouse lens impairs fibroblast growth factor receptor signalingDifferential binding of Lef1 and Msx1/2 transcription factors to Dkk1 CNEs correlates with reporter gene expression in vivoAdvances in multicellular spheroids formationGene expression profiles of lens regeneration and development in Xenopus laevis.Secreted frizzled-related protein disrupts PCP in eye lens fiber cells that have polarised primary ciliaTransdifferentiation from cornea to lens in Xenopus laevis depends on BMP signalling and involves upregulation of Wnt signallingEfficient generation of lens progenitor cells and lentoid bodies from human embryonic stem cells in chemically defined conditions.Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development.Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension.Cell signaling pathways in vertebrate lens regeneration.Molecular mechanism of formation of cortical opacity in CRYAAN101D transgenic mice.Cell-autonomous requirements for Dlg-1 for lens epithelial cell structure and fiber cell morphogenesis.Understanding the role of growth factors in embryonic development: insights from the lensThe cellular and molecular mechanisms of vertebrate lens development.The effect of maternal diabetes on the Wnt-PCP pathway during embryogenesis as reflected in the developing mouse eye.Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival.Conditional ablation of the Notch2 receptor in the ocular lens.Wnt-frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation.Lens regeneration from the cornea requires suppression of Wnt/β-catenin signaling.Loss of Axin2 Causes Ocular Defects During Mouse Eye DevelopmentSfrp1 and Sfrp2 are not involved in Wnt/β-catenin signal silencing during lens induction but are required for maintenance of Wnt/β-catenin signaling in lens epithelial cells.Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens.The membrane proteome of the mouse lens fiber cell.The lens in focus: a comparison of lens development in Drosophila and vertebrates.Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism.Molecular and cellular aspects of amphibian lens regeneration.The lens equator: a platform for molecular machinery that regulates the switch from cell proliferation to differentiation in the vertebrate lens.Comparative transcriptome analysis of epithelial and fiber cells in newborn mouse lenses with RNA sequencing.The lens actin filament cytoskeleton: Diverse structures for complex functions.The molecular mechanisms underlying lens fiber elongation.Intrinsic and extrinsic regulatory mechanisms are required to form and maintain a lens of the correct size and shape.The lens growth process.Microtubules enable the planar cell polarity of airway cilia.Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death.Analysis of PCP defects in mammalian eye lens.The klotho-related protein KLPH (lctl) has preferred expression in lens and is essential for expression of clic5 and normal lens suture formation.
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Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 September 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Wnt signaling is required for ...... three-dimensional architecture
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Wnt signaling is required for ...... hree-dimensional architecture.
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type
label
Wnt signaling is required for ...... three-dimensional architecture
@en
Wnt signaling is required for ...... hree-dimensional architecture.
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prefLabel
Wnt signaling is required for ...... three-dimensional architecture
@en
Wnt signaling is required for ...... hree-dimensional architecture.
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P2093
P2860
P1476
Wnt signaling is required for ...... three-dimensional architecture
@en
P2093
Akihiko Shimono
Frank J Lovicu
John W McAvoy
Richard J W Stump
Yongjuan Chen
P2860
P304
P356
10.1016/J.YDBIO.2008.09.002
P407
P577
2008-09-18T00:00:00Z