Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1. - Wikidata - awgldk - TriplyDB

Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1.

Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1.

http://www.wikidata.org/entity/Q37118372

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Neurotropin suppresses inflammatory cytokine expression and cell death through suppression of NF-κB and JNK in hepatocytes Branched-chain amino acids prevent hepatic fibrosis and development of hepatocellular carcinoma in a non-alcoholic steatohepatitis mouse model.Hepatocyte-specific expression of constitutively active Alk5 exacerbates thioacetamide-induced liver injury in mice.TGF-β-induced hepatocyte lincRNA-p21 contributes to liver fibrosis in mice TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis Bone morphogenetic protein signaling protects against cerulein-induced pancreatic fibrosis.Increased Expression of TGF-β Signaling Components in a Mouse Model of Fibrosis Induced by Submandibular Gland Duct Ligation.Hepatic stellate cells: central modulators of hepatic carcinogenesis.Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice.Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish.In vivo gene manipulation reveals the impact of stress-responsive MAPK pathways on tumor progression.Dual actions of a novel bifunctional compound to lower glucose in mice with diet-induced insulin resistance CCR7 enhances TGF-β1-induced epithelial-mesenchymal transition and is associated with lymph node metastasis and poor overall survival in gastric cancer.A novel role of hepatic epithelial transforming growth factor-β signaling in cholangiocarcinogenesis.TGFβ signaling: a friend or a foe to hepatic fibrosis and tumorigenesis.TAK1 regulates hepatic lipid homeostasis through SREBP Role of BMSCs in liver regeneration and metastasis after hepatectomy.Fibroblast growth factor receptor 3 interacts with and activates TGFβ-activated kinase 1 tyrosine phosphorylation and NFκB signaling in multiple myeloma and bladder cancer.Transforming growth factor β-activated kinase 1 transcriptionally suppresses hepatitis B virus replication.Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice NCOA5, IL-6, type 2 diabetes, and HCC: The deadly quartet.TGF-β Mediated Crosstalk Between Malignant Hepatocyte and Tumor Microenvironment in Hepatocellular Carcinoma.TAK1 regulates hepatic cell survival and carcinogenesis.TNFα in liver fibrosis.IL6-mediated inflammatory loop reprograms normal to epithelial-mesenchymal transition+ metastatic cancer stem cells in preneoplastic liver of transforming growth factor beta-deficient β2-spectrin+/- mice.Functional characterization of AMP-activated protein kinase signaling in tumorigenesis.Biomarkers in hepatocellular carcinoma: an overview.MicroRNA-101 suppresses liver fibrosis by targeting the TGFβ signalling pathway.The contribution of toll-like receptor signaling to the development of liver fibrosis and cancer in hepatocyte-specific TAK1-deleted mice.Evaluating the antifibrotic potency of galunisertib in a human ex vivo model of liver fibrosis.The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis.Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis.Involvement of epithelial-mesenchymal transition in liver fibrosis.Transforming growth factor-β in liver cancer stem cells and regeneration.Myeloid-specific TAK1 deletion results in reduced brain monocyte infiltration and improved outcomes after stroke.

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Transforming growth factor-β signaling in hepatocytes promotes hepatic fibrosis and carcinogenesis in mice with hepatocyte-specific deletion of TAK1.

http://www.wikidata.org/entity/Q37118372

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 04 February 2013

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Transforming growth factor-β s ...... yte-specific deletion of TAK1.

@en

Transforming growth factor-β s ...... yte-specific deletion of TAK1.

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type

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Transforming growth factor-β s ...... yte-specific deletion of TAK1.

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Transforming growth factor-β s ...... yte-specific deletion of TAK1.

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Transforming growth factor-β s ...... yte-specific deletion of TAK1.

@en

Transforming growth factor-β s ...... yte-specific deletion of TAK1.

@nl

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J.GASTRO.2013.01.056

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Gastroenterology

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Transforming growth factor-β s ...... yte-specific deletion of TAK1.

@en

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Eek Joong Park

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Ekihiro Seki

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Jingyi Song

http://www.w3.org/2001/XMLSchema#string

Ling Yang

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Rohit Loomba

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Sayaka Inokuchi

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Yoon Seok Roh

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P2860

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TGF-beta signaling in tumor suppression and cancer progression

Elucidation of a universal size-control mechanism in Drosophila and mammals

Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma.

Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis.

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1042-1054.e4

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scholarly article

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10.1053/J.GASTRO.2013.01.056

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