Elucidation of Acquired Resistance to Bcl-2 and MDM2 Inhibitors in Acute Leukemia In Vitro and In Vivo.

Elucidation of Acquired Resistance to Bcl-2 and MDM2 Inhibitors in Acute Leukemia In Vitro and In Vivo.

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http://www.wikidata.org/entity/Q37118668
Significant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug TreatmentMDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer.A natural product-like JAK2/STAT3 inhibitor induces apoptosis of malignant melanoma cells.c9, t11- conjugated linoleic acid induces HCC cell apoptosis and correlation with PPAR-γ signaling pathway.Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress.MDM2 Inhibition Sensitizes Prostate Cancer Cells to Androgen Ablation and Radiotherapy in a p53-Dependent Manner.Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapy: Progress and Challenges.The BH3 mimetic drug ABT-737 induces apoptosis and acts synergistically with chemotherapeutic drugs in thyroid carcinoma cells.Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/- mouse model.Targeted Degradation of BET Proteins in Triple-Negative Breast Cancer.
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Elucidation of Acquired Resistance to Bcl-2 and MDM2 Inhibitors in Acute Leukemia In Vitro and In Vivo.

Item
http://www.wikidata.org/entity/Q37118668
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 09 March 2015
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Elucidation of Acquired Resist ...... Leukemia In Vitro and In Vivo.
@en
Elucidation of Acquired Resist ...... Leukemia In Vitro and In Vivo.
@nl
type
label
Elucidation of Acquired Resist ...... Leukemia In Vitro and In Vivo.
@en
Elucidation of Acquired Resist ...... Leukemia In Vitro and In Vivo.
@nl
prefLabel
Elucidation of Acquired Resist ...... Leukemia In Vitro and In Vivo.
@en
Elucidation of Acquired Resist ...... Leukemia In Vitro and In Vivo.
@nl
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Elucidation of Acquired Resist ...... Leukemia In Vitro and In Vivo
@en
P2093
P2860
P304
P31
P356
10.1158/1078-0432.CCR-14-2506
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P433
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P50
P577
P698
P921
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