The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men - Wikidata - awgldk - TriplyDB

The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men

The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men

http://www.wikidata.org/entity/Q37118904

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The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formation Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model Smelling the roses and seeing the light: gene therapy for ciliopathies The primary cilium as a dual sensor of mechanochemical signals in chondrocytes Cilia/Ift protein and motor -related bone diseases and mouse models Axonemal positioning and orientation in three-dimensional space for primary cilia: what is known, what is assumed, and what needs clarification Wnt and planar cell polarity signaling in cystic renal disease A Cilia Independent Role of Ift88/Polaris during Cell Migration The nonmotile ciliopathies.Architecture and function of IFT complex proteins in ciliogenesis SCO-ping out the mechanisms underlying the etiology of hydrocephalus Cranioectodermal Dysplasia, Sensenbrenner syndrome, is a ciliopathy caused by mutations in the IFT122 gene Role of epidermal primary cilia in the homeostasis of skin and hair follicles A novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalus The primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiation Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium Knockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells and the pronephros in zebrafish GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail Directional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblasts A mutation in the mouse ttc26 gene leads to impaired hedgehog signaling The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch Molecular advances in autosomal dominant polycystic kidney disease.Cluap1 is essential for ciliogenesis and photoreceptor maintenance in the vertebrate eye.Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway Cilia in the CNS: the quiet organelle claims center stage Epidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger.The fate of bone marrow-derived cells carrying a Polycystic Kidney Disease mutation in the genetically normal kidney Soluble levels of cytosolic tubulin regulate ciliary length control Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease Non-essential role for cilia in coordinating precise alignment of lens fibres.Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.The primary cilium at a glance Case study: polycystic livers in a transgenic mouse line Polycystic kidney disease: pathogenesis and potential therapies.Autosomal dominant polycystic kidney disease: recent advances in pathogenesis and potential therapies.Mouse models of polycystic kidney disease induced by defects of ciliary proteins Hair curvature: a natural dialectic and review.The cilium: a cellular antenna with an influence on obesity risk.Functional Study of the Primary Cilia in ADPKD.Validation of Effective Therapeutic Targets for ADPKD Using Animal Models.

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The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men

http://www.wikidata.org/entity/Q37118904

description

article científic

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article scientifique

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artigo científico

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bilimsel makale

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scientific article published on August 2008

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men

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The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men.

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type

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The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men

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The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men.

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The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men

@en

The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men.

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Developmental Dynamics

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The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men

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Bradley K Yoder

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Edward J Michaud

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Michael Miller

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Trenton R Schoeb

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P2860

Gli2 and Gli3 localize to cilia and require the intraflagellar transport protein polaris for processing and function

Mutations in a new gene in Ellis-van Creveld syndrome and Weyers acrodental dysostosis

The Ciliopathies: An Emerging Class of Human Genetic Disorders

Dissection of epistasis in oligogenic Bardet-Biedl syndrome

Primary ciliary dyskinesia associated with normal axoneme ultrastructure is caused by DNAH11 mutations

Mutations in the gene encoding the basal body protein RPGRIP1L, a nephrocystin-4 interactor, cause Joubert syndrome

The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal syndrome (Joubert syndrome type B) and Meckel syndrome

The centrosomal protein nephrocystin-6 is mutated in Joubert syndrome and activates transcription factor ATF4

A motility in the eukaryotic flagellum unrelated to flagellar beating

Polaris, a protein involved in left-right axis patterning, localizes to basal bodies and cilia

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1960-1971

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scholarly article

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10.1002/DVDY.21515

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8

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237

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Jonathan Merle Lehman

Yesim Aydin-Son

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2008-08-01T00:00:00Z

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5486571

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18366137

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autosomal dominant polycystic kidney disease

Chin-hu̍t seng-bu̍t

biomedical investigative technique

neoplasm proteins

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2677030

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