The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men
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The Talpid3 gene (KIAA0586) encodes a centrosomal protein that is essential for primary cilia formationGene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy modelSmelling the roses and seeing the light: gene therapy for ciliopathiesThe primary cilium as a dual sensor of mechanochemical signals in chondrocytesCilia/Ift protein and motor -related bone diseases and mouse modelsAxonemal positioning and orientation in three-dimensional space for primary cilia: what is known, what is assumed, and what needs clarificationWnt and planar cell polarity signaling in cystic renal diseaseA Cilia Independent Role of Ift88/Polaris during Cell MigrationThe nonmotile ciliopathies.Architecture and function of IFT complex proteins in ciliogenesisSCO-ping out the mechanisms underlying the etiology of hydrocephalusCranioectodermal Dysplasia, Sensenbrenner syndrome, is a ciliopathy caused by mutations in the IFT122 geneRole of epidermal primary cilia in the homeostasis of skin and hair folliclesA novel murine allele of Intraflagellar Transport Protein 172 causes a syndrome including VACTERL-like features with hydrocephalusThe primary cilium coordinates early cardiogenesis and hedgehog signaling in cardiomyocyte differentiationPrimary cilia dynamics instruct tissue patterning and repair of corneal endotheliumKnockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells and the pronephros in zebrafishGMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tailDirectional cell migration and chemotaxis in wound healing response to PDGF-AA are coordinated by the primary cilium in fibroblastsA mutation in the mouse ttc26 gene leads to impaired hedgehog signalingThe zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretchMolecular advances in autosomal dominant polycystic kidney disease.Cluap1 is essential for ciliogenesis and photoreceptor maintenance in the vertebrate eye.Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathwayCilia in the CNS: the quiet organelle claims center stageEpidermal growth factor-induced proliferation of collecting duct cells from Oak Ridge polycystic kidney mice involves activation of Na+/H+ exchanger.The fate of bone marrow-derived cells carrying a Polycystic Kidney Disease mutation in the genetically normal kidneySoluble levels of cytosolic tubulin regulate ciliary length controlActivation of the intrarenal renin-angiotensin-system in murine polycystic kidney diseaseNon-essential role for cilia in coordinating precise alignment of lens fibres.Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.The primary cilium at a glanceCase study: polycystic livers in a transgenic mouse linePolycystic kidney disease: pathogenesis and potential therapies.Autosomal dominant polycystic kidney disease: recent advances in pathogenesis and potential therapies.Mouse models of polycystic kidney disease induced by defects of ciliary proteinsHair curvature: a natural dialectic and review.The cilium: a cellular antenna with an influence on obesity risk.Functional Study of the Primary Cilia in ADPKD.Validation of Effective Therapeutic Targets for ADPKD Using Animal Models.
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P2860
The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men
@en
The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men.
@nl
type
label
The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men
@en
The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men.
@nl
prefLabel
The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men
@en
The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men.
@nl
P2093
P2860
P921
P356
P1476
The Oak Ridge Polycystic Kidney mouse: modeling ciliopathies of mice and men
@en
P2093
Bradley K Yoder
Edward J Michaud
Michael Miller
Trenton R Schoeb
P2860
P304
P356
10.1002/DVDY.21515
P577
2008-08-01T00:00:00Z