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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other lociHuman factor H deficiency. Mutations in framework cysteine residues and block in H protein secretion and intracellular catabolismA common haplotype in the complement regulatory gene factor H (HF1/CFH) predisposes individuals to age-related macular degenerationC-Reactive protein binds to apoptotic cells, protects the cells from assembly of the terminal complement components, and sustains an antiinflammatory innate immune response: implications for systemic autoimmunityLinks between complement deficiency and apoptosis.Complement activation is required for induction of a protective antibody response against West Nile virus infectionThe endothelial deprotection hypothesis for lupus pathogenesis: the dual role of C1q as a mediator of clearance and regulator of endothelial permeabilityComplement C5 in experimental autoimmune encephalomyelitis (EAE) facilitates remyelination and prevents gliosis.The extracellular matrix and inflammation: fibromodulin activates the classical pathway of complement by directly binding C1q.Reconstitution of the alternative pathway of complement by plasma infusions given to a patient with an SLE-like syndrome associated with a hereditary C3 dysfunctionMorbidity study of extruder personnel with potential exposure to brominated dioxins and furans. I. Results of blood monitoring and immunological tests.Human lupus autoantibody-DNA complexes activate DCs through cooperation of CD32 and TLR9.Importance of antibody and complement for oxidative burst and killing of invasive nontyphoidal Salmonella by blood cells in AfricansProperdin deficiency and meningococcal disease--identifying those most at risk.Links between complement abnormalities and systemic lupus erythematosus.A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo.Dating the primigenial C4-CYP21 duplication in primates.Lupus susceptibility genes on human chromosome 1.Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degenerationAn extensive screen of the HLA region reveals an independent association of HLA class I and class II with susceptibility for systemic lupus erythematosus.Recent insights into the genetic basis of systemic lupus erythematosusAccelerated development of IgG autoantibodies and autoimmune disease in the absence of secreted IgM.Anaemia & expression levels of CD35, CD55 & CD59 on red blood cells in Plasmodium falciparum malaria patients from India.NC4 Domain of cartilage-specific collagen IX inhibits complement directly due to attenuation of membrane attack formation and indirectly through binding and enhancing activity of complement inhibitors C4B-binding protein and factor H.Complement and lupus: old concepts and new directions.B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-alphaGAL-producing B-1 cellsComplement receptor 1 (CR1) expression in chronic myeloid leukemia.Beyond C4d: other complement-related diagnostic approaches to antibody-mediated rejection.A novel blood-based biomarker for detection of autism spectrum disordersA protective role for innate immunity in systemic lupus erythematosus.Role of MHC-linked susceptibility genes in the pathogenesis of human and murine lupus.High complement factor I activity in the plasma of children with autism spectrum disorders.Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes.Genetics of SLE: functional relevance for monocytes/macrophages in diseaseAutoimmunity: basic mechanisms and implications in endocrine diseases. Part I.Structural stability and heat-induced conformational change of two complement inhibitors: C4b-binding protein and factor HThe role of CR2 in autoimmunity.CRP and the disposal of dying cells: consequences for systemic lupus erythematosus and rheumatoid arthritis.Malaria inhibits surface expression of complement receptor 1 in monocytes/macrophages, causing decreased immune complex internalization.Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Complement deficiency and disease.
@en
type
label
Complement deficiency and disease.
@en
prefLabel
Complement deficiency and disease.
@en
P1433
P1476
Complement deficiency and disease.
@en
P2093
P304
P356
10.1016/0167-5699(91)90003-C
P50
P577
1991-09-01T00:00:00Z