Different response of human glioma tumor-initiating cells to epidermal growth factor receptor kinase inhibitors.
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In vitro and in vivo characterization of highly purified human mesothelioma derived cellsMolecular biomarkers of cancer stem/progenitor cells associated with progression, metastases, and treatment resistance of aggressive cancersTargeting glioma stem cells: a novel framework for brain tumorsEGFR inhibition in glioma cells modulates Rho signaling to inhibit cell motility and invasion and cooperates with temozolomide to reduce cell growthDelineating the cytogenomic and epigenomic landscapes of glioma stem cell linesCXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment.Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cellsPotential therapeutic implications of cancer stem cells in glioblastomaNew promising drug targets in cancer- and metastasis-initiating cells.Targeting cancer stem cell plasticity through modulation of epidermal growth factor and insulin-like growth factor receptor signaling in head and neck squamous cell cancer.CXCR4 expression in feline mammary carcinoma cells: evidence of a proliferative role for the SDF-1/CXCR4 axis.Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies.Two mature products of MIR-491 coordinate to suppress key cancer hallmarks in glioblastoma.Novel therapies against aggressive and recurrent epithelial cancers by molecular targeting tumor- and metastasis-initiating cells and their progenies.New advances on critical implications of tumor- and metastasis-initiating cells in cancer progression, treatment resistance and disease recurrenceIdentification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells.Multi-scale agent-based brain cancer modeling and prediction of TKI treatment response: incorporating EGFR signaling pathway and angiogenesisMetformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion currentDifferential distribution of erbB receptors in human glioblastoma multiforme: expression of erbB3 in CD133-positive putative cancer stem cells.In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors2-Hydroxyoleate, a nontoxic membrane binding anticancer drug, induces glioma cell differentiation and autophagy.Activation of multiple ERBB family receptors mediates glioblastoma cancer stem-like cell resistance to EGFR-targeted inhibition.Preclinical studies identify novel targeted pharmacological strategies for treatment of human malignant pleural mesothelioma.Complex oncogenic signaling networks regulate brain tumor-initiating cells and their progenies: pivotal roles of wild-type EGFR, EGFRvIII mutant and hedgehog cascades and novel multitargeted therapies.Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells.Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures.Essential gene pathways for glioblastoma stem cells: clinical implications for prevention of tumor recurrence.Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain.Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells.Abrogation of mitogen-activated protein kinase and Akt signaling by vandetanib synergistically potentiates histone deacetylase inhibitor-induced apoptosis in human glioma cells.Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cellsTargeting CD133 antigen in cancer.Down-modulation of SEL1L, an unfolded protein response and endoplasmic reticulum-associated degradation protein, sensitizes glioma stem cells to the cytotoxic effect of valproic acid.Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies.Signaling in malignant astrocytomas: role of neural stem cells and its therapeutic implications.Targeted therapy in the treatment of malignant gliomasCancer stem cells in glioblastoma--molecular signaling and therapeutic targeting.Cancer stem cells: the development of new cancer therapeutics.MicroRNAs as regulators of neural stem cell-related pathways in glioblastoma multiforme.
P2860
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P2860
Different response of human glioma tumor-initiating cells to epidermal growth factor receptor kinase inhibitors.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 January 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Different response of human gl ...... or receptor kinase inhibitors.
@en
Different response of human gl ...... or receptor kinase inhibitors.
@nl
type
label
Different response of human gl ...... or receptor kinase inhibitors.
@en
Different response of human gl ...... or receptor kinase inhibitors.
@nl
prefLabel
Different response of human gl ...... or receptor kinase inhibitors.
@en
Different response of human gl ...... or receptor kinase inhibitors.
@nl
P2093
P2860
P4510
P356
P1476
Different response of human gl ...... or receptor kinase inhibitors.
@en
P2093
Adriana Bajetto
Alessandra Pattarozzi
Alice Melotti
Antonio Daga
Carola Porcile
Daniela Marubbi
Fabrizio Griffero
Federica Barbieri
Gianluigi Zona
Giorgio Corte
P2860
P304
P356
10.1074/JBC.M807111200
P407
P577
2009-01-14T00:00:00Z