Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase
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Reactive Oxygen Species-Mediated Mechanisms of Action of Targeted Cancer TherapyDiverse Redoxome Reactivity Profiles of Carbon Nucleophiles.DUOX1 mediates persistent epithelial EGFR activation, mucous cell metaplasia, and airway remodeling during allergic asthma.Privileged Electrophile Sensors: A Resource for Covalent Drug Development.Bound by Fate: The Role of Reactive Oxygen Species in Receptor-Like Kinase Signaling.Hepatostat: Liver regeneration and normal liver tissue maintenance.Paradoxical roles of dual oxidases in cancer biology.Cysteine perthiosulfenic acid (Cys-SSOH): A novel intermediate in thiol-based redox signaling?The NADPH Oxidases DUOX1 and NOX2 Play Distinct Roles in Redox Regulation of Epidermal Growth Factor Receptor Signaling.Self-Cyclizing Antioxidants to Prevent DNA Damage Caused by Hydroxyl Radical.The role of sulfenic acids in cellular redox signaling: Reconciling chemical kinetics and molecular detection strategies.Chemical methods for mapping cysteine oxidation.A role for 2-Cys peroxiredoxins in facilitating cytosolic protein thiol oxidation.The interplay of reactive oxygen species and the epidermal growth factor receptor in tumor progression and drug resistance.Mitochondria-targeted Probes for Imaging Protein Sulfenylation.L718Q mutant EGFR escapes covalent inhibition by stabilizing a non-reactive conformation of the lung cancer drug osimertinib.Direct cysteine sulfenylation drives activation of the Src kinase
P2860
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P2860
Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on July 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase
@en
Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase.
@nl
type
label
Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase
@en
Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase.
@nl
prefLabel
Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase
@en
Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase.
@nl
P2093
P2860
P1476
Molecular Basis for Redox Activation of Epidermal Growth Factor Receptor Kinase
@en
P2093
Avner Schlessinger
Candice E Paulsen
Prakash B Palde
Thu H Truong
P2860
P304
P356
10.1016/J.CHEMBIOL.2016.05.017
P577
2016-07-01T00:00:00Z