A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls.

A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls.

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http://www.wikidata.org/entity/Q37122270

Q37122270

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Micro spies from the brain to the periphery: new clues from studies on microRNAs in neuropsychiatric disorders Frontotemporal Lobar Degeneration and MicroRNAs Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease Circulating microRNAs in Alzheimer's disease: the search for novel biomarkers Alteration of the microRNA network during the progression of Alzheimer's disease.Widespread microRNA dysregulation in multiple system atrophy - disease-related alteration in miR-96.MicroRNAs targeting Nicastrin regulate Aβ production and are affected by target site polymorphisms The emerging roles of microRNAs in the pathogenesis of frontotemporal dementia-amyotrophic lateral sclerosis (FTD-ALS) spectrum disorders Epigenomics of Alzheimer's disease.Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia.Soluble beta-amyloid peptides, but not insoluble fibrils, have specific effect on neuronal microRNA expression.The TMEM106B locus and TDP-43 pathology in older persons without FTLD Plasma Exosomal miRNAs in Persons with and without Alzheimer Disease: Altered Expression and Prospects for Biomarkers.Novel microRNA discovery using small RNA sequencing in post-mortem human brain.Evidence for a neuroprotective microRNA pathway in amnestic mild cognitive impairment.miR-132/212 deficiency impairs tau metabolism and promotes pathological aggregation in vivo.Mutation in the 3'untranslated region of APP as a genetic determinant of cerebral amyloid angiopathy.Preclinical Evaluation of miR-15/107 Family Members as Multifactorial Drug Targets for Alzheimer's Disease Plasma microRNA biomarkers for detection of mild cognitive impairment: biomarker validation study.MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects Expression of miR-15/107 family microRNAs in human tissues and cultured rat brain cells."New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).miRNA-dependent target regulation: functional characterization of single-nucleotide polymorphisms identified in genome-wide association studies of Alzheimer's disease miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain.microRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer's disease triple transgenic mice.Identification of age- and disease-related alterations in circulating miRNAs in a mouse model of Alzheimer's disease.Transcriptome-wide piRNA profiling in human brains of Alzheimer's disease.MicroRNA expression patterns in human anterior cingulate and motor cortex: A study of dementia with Lewy bodies cases and controls.Regional and subtype-dependent miRNA signatures in sporadic Creutzfeldt-Jakob disease are accompanied by alterations in miRNA silencing machinery and biogenesis.Whole transcriptome profiling of Late-Onset Alzheimer's Disease patients provides insights into the molecular changes involved in the disease.Supplemental Treatment for Huntington's Disease with miR-132 that Is Deficient in Huntington's Disease Brain.

P2860

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P2860

A study of small RNAs from cerebral neocortex of pathology-verified Alzheimer's disease, dementia with lewy bodies, hippocampal sclerosis, frontotemporal lobar dementia, and non-demented human controls.

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http://www.wikidata.org/entity/Q37122270

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article científic

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article scientifique

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artigo científico

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bilimsel makale

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scientific article published on January 2013

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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