Heritability and genome-wide linkage in US and australian twins identify novel genomic regions controlling chromogranin a: implications for secretion and blood pressure.
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The Brisbane Systems Genetics Study: genetical genomics meets complex trait geneticsThe emerging role of non-coding RNA in essential hypertension and blood pressure regulation.microRNAs in Essential Hypertension and Blood Pressure Regulation.Secretory granules in inositol 1,4,5-trisphosphate-dependent Ca2+ signaling in the cytoplasm of neuroendocrine cells.Catestatin: a multifunctional peptide from chromogranin AA common genetic variant in the 3'-UTR of vacuolar H+-ATPase ATP6V0A1 creates a micro-RNA motif to alter chromogranin A processing and hypertension riskCardiac electrical activity in a genomically "humanized" chromogranin a monogenic mouse model with hyperadrenergic hypertensionUrocortin 2 lowers blood pressure and reduces plasma catecholamine levels in mice with hyperadrenergic activity.Effects of chromogranin A deficiency and excess in vivo: biphasic blood pressure and catecholamine responsesThe myriad essential roles of microRNAs in cardiovascular homeostasis and disease.Chromogranin/secretogranin proteins in murine heart: myocardial production of chromogranin A fragment catestatin (Chga(364-384))Catestatin improves post-ischemic left ventricular function and decreases ischemia/reperfusion injury in heart.Direct vasoactive effects of the chromogranin A (CHGA) peptide catestatin in humans in vivo.Catestatin exerts direct protective effects on rat cardiomyocytes undergoing ischemia/reperfusion by stimulating PI3K-Akt-GSK3β pathway and preserving mitochondrial membrane potentialProteomic analysis yields an unexpected trans-acting point in control of the human sympathochromaffin phenotype.Differential expression of hypertension-associated microRNAs in the plasma of patients with white coat hypertensionTwins for epigenetic studies of human aging and developmentNovel peptide isomer strategy for stable inhibition of catecholamine release: application to hypertensionThe extended granin family: structure, function, and biomedical implicationsDissecting complex phenotypes using the genomics of twins.Genetic variation within a metabolic motif in the chromogranin a promoter: pleiotropic influence on cardiometabolic risk traits in twins.Chromogranin A regulates renal function by triggering Weibel-Palade body exocytosis.Natural variation within the neuronal nicotinic acetylcholine receptor cluster on human chromosome 15q24: influence on heritable autonomic traits in twin pairs.Cardiac resynchronization therapy for the treatment of sleep apnoea: a meta-analysis.MicroRNAs in hypertension: mechanisms and therapeutic targets.The surging role of Chromogranin A in cardiovascular homeostasis.Chromogranin A Regulation of Obesity and Peripheral Insulin Sensitivity.Analysis and validation of traits associated with a single nucleotide polymorphism Gly364Ser in catestatin using humanized chromogranin A mouse models.Phosphodiesterase type-2 and NO-dependent S-nitrosylation mediate the cardioinhibition of the antihypertensive catestatin.Identification of novel loci affecting circulating chromogranins and related peptides.Mammary epithelium-specific inactivation of V-ATPase reduces stiffness of extracellular matrix and enhances metastasis of breast cancer.Circulating chromogranin A and its fragments as diagnostic and prognostic disease markers.Role of the neuroendocrine antimicrobial peptide catestatin in innate immunity and pain.Common genetic variation in the 3'-untranslated region of gonadotropin-releasing hormone receptor regulates gene expression in cella and is associated with thyroid function, insulin secretion as well as insulin sensitivity in polycystic ovary syndroGlobal identification of the genes and pathways differentially expressed in hypothalamus in early and established neurogenic hypertension.Catestatin as a Target for Treatment of Inflammatory DiseasesVacuolar H+-ATPase: An Essential Multitasking Enzyme in Physiology and Pathophysiology
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P2860
Heritability and genome-wide linkage in US and australian twins identify novel genomic regions controlling chromogranin a: implications for secretion and blood pressure.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 30 June 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Heritability and genome-wide l ...... secretion and blood pressure.
@en
Heritability and genome-wide l ...... secretion and blood pressure.
@nl
type
label
Heritability and genome-wide l ...... secretion and blood pressure.
@en
Heritability and genome-wide l ...... secretion and blood pressure.
@nl
prefLabel
Heritability and genome-wide l ...... secretion and blood pressure.
@en
Heritability and genome-wide l ...... secretion and blood pressure.
@nl
P2093
P2860
P50
P1433
P1476
Heritability and genome-wide l ...... secretion and blood pressure.
@en
P2093
Daniel T O'Connor
Fangwen Rao
John B Whitfield
Kuixing Zhang
Madhusudan Das
Manjula Mahata
Maple M Fung
Mats Stridsberg
P2860
P304
P356
10.1161/CIRCULATIONAHA.107.709105
P407
P577
2008-06-30T00:00:00Z