Inhibition of polo-like kinase 1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitisation
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PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase.Genome-wide functional genomic and transcriptomic analyses for genes regulating sensitivity to vorinostat.Targeting MPS1 Enhances Radiosensitization of Human Glioblastoma by Modulating DNA Repair ProteinsCaveolin-1 is Associated with Tumor Progression and Confers a Multi-Modality Resistance Phenotype in Pancreatic Cancer.Targeting Polo-Like Kinases: A Promising Therapeutic Approach for Cancer TreatmentA genome scale RNAi screen identifies GLI1 as a novel gene regulating vorinostat sensitivity.Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating CellsModulation of miR-21 signaling by MPS1 in human glioblastomaBlockade of vascular endothelial growth factor receptors by tivozanib has potential anti-tumour effects on human glioblastoma cellsGamma histone 2AX (γ-H2AX)as a predictive tool in radiation oncology.Radiosensitization in esophageal squamous cell carcinoma: Effect of polo-like kinase 1 inhibition.Identification of AREG and PLK1 pathway modulation as a potential key of the response of intracranial 9L tumor to microbeam radiation therapy.Survival kinase genes present prognostic significance in glioblastoma.CDC20 with malignant progression and poor prognosis of astrocytoma revealed by analysis on gene expression.A novel stem cell culture model of recurrent glioblastoma.The polo-like kinase 1 inhibitor volasertib synergistically increases radiation efficacy in glioma stem cells.DNA-PKcs associates with PLK1 and is involved in proper chromosome segregation and cytokinesis.
P2860
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P2860
Inhibition of polo-like kinase 1 in glioblastoma multiforme induces mitotic catastrophe and enhances radiosensitisation
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 June 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Inhibition of polo-like kinase ...... nd enhances radiosensitisation
@en
Inhibition of polo-like kinase ...... d enhances radiosensitisation.
@nl
type
label
Inhibition of polo-like kinase ...... nd enhances radiosensitisation
@en
Inhibition of polo-like kinase ...... d enhances radiosensitisation.
@nl
prefLabel
Inhibition of polo-like kinase ...... nd enhances radiosensitisation
@en
Inhibition of polo-like kinase ...... d enhances radiosensitisation.
@nl
P2093
P2860
P1476
Inhibition of polo-like kinase ...... nd enhances radiosensitisation
@en
P2093
Aditya Halthore
Anita T Tandle
Kevin Camphausen
Kristen Gehlhaus
Natasha J Caplen
Philip J Tofilon
Tamalee Kramp
Uma Shankavaram
Whoon J Kil
P2860
P304
P356
10.1016/J.EJCA.2013.05.013
P577
2013-06-18T00:00:00Z