Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors

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Tetracycline-Inactivating Enzymes.

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Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors

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article científic

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article scientifique

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bilimsel makale

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scientific article published on 05 July 2016

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Resistance mutations generate ...... against translation inhibitors

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Resistance mutations generate ...... gainst translation inhibitors.

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Resistance mutations generate ...... against translation inhibitors

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Resistance mutations generate ...... gainst translation inhibitors.

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Resistance mutations generate ...... against translation inhibitors

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Resistance mutations generate ...... gainst translation inhibitors.

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Resistance mutations generate ...... against translation inhibitors

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Alexis I Cocozaki

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Andrew D Ferguson

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D Bryan Prince

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Ed T Buurman

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Jamie H D Cate

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Jian Huang

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Peter Doig

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Steven L Kazmirski

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Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.

Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant

Structures of the ribosome in intermediate states of ratcheting

Structural aspects of messenger RNA reading frame maintenance by the ribosome

Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis

Exploiting structure similarity in refinement: automated NCS and target-structure restraints in BUSTER

Crystal Structures of EF-G-Ribosome Complexes Trapped in Intermediate States of Translocation

Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin

4′-O-substitutions determine selectivity of aminoglycoside antibiotics

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8188-8193

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scholarly article

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10.1073/PNAS.1605127113

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English

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113

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Scott C Blanchard

Russ Altman

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2016-07-05T00:00:00Z

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27382179

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antibiotic resistance

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4961145

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Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors

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Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors

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P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932