Dual-functional abeo-taxane derivatives destabilizing microtubule equilibrium and inhibiting NF-κB activation

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Dual-functional abeo-taxane derivatives destabilizing microtubule equilibrium and inhibiting NF-κB activation

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 31 May 2013

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vedecký článok

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vetenskaplig artikel

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Dual-functional abeo-taxane de ...... nd inhibiting NF-κB activation

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Dual-functional abeo-taxane de ...... d inhibiting NF-κB activation.

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Dual-functional abeo-taxane de ...... nd inhibiting NF-κB activation

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Dual-functional abeo-taxane de ...... d inhibiting NF-κB activation.

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Dual-functional abeo-taxane de ...... nd inhibiting NF-κB activation

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Dual-functional abeo-taxane de ...... d inhibiting NF-κB activation.

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P1476

Dual-functional abeo-taxane de ...... nd inhibiting NF-κB activation

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Jia Su

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Kuo-Hsiung Lee

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Masuo Goto

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Qin-Shi Zhao

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Susan L Morris-Natschke

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Yan Li

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Yu Zhao

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Zhu-Jun Yao

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Antitumor agents. 284. New desmosdumotin B analogues with bicyclic B-ring as cytotoxic and antitubulin agents.

Biological activity and chemistry of taxoids from the Japanese yew, Taxus cuspidata.

Anticancer drugs from nature--natural products as a unique source of new microtubule-stabilizing agents.

Bridging converts a noncytotoxic nor-paclitaxel derivative to a cytotoxic analogue by constraining it to the T-Taxol conformation.

From single- to multi-target drugs in cancer therapy: when aspecificity becomes an advantage.

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4749-4757

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scholarly article

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10.1021/JM400479P

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English

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P478

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2013-05-31T00:00:00Z

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23725535

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NF-κB

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3755589

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