Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation. - Wikidata - awgldk - TriplyDB

Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.

Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.

http://www.wikidata.org/entity/Q37130129

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Nuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet?Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice Clinical application of transcriptional activators of bile salt transporters.Curcumin attenuates cardiac fibrosis in spontaneously hypertensive rats through PPAR-γ activation.NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.Protective effects of curcumin in APPswe transfected SH-SY5Y cells Congenital hepatic fibrosis in autosomal recessive polycystic kidney disease.Nuclear receptors as drug targets in cholestatic liver diseases.Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output Curcumin protects ANIT-induced cholestasis through signaling pathway of FXR-regulated bile acid and inflammation.Protective effects of a natural product, curcumin, against amyloid β induced mitochondrial and synaptic toxicities in Alzheimer's disease.Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis.Peroxisome proliferator activating receptor (PPAR) in cerebral malaria (CM): a novel target for an additional therapy.Therapeutic potential of curcumin in gastrointestinal diseases.Role of nuclear receptors in the biliary epithelium.The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies.Animal models in primary biliary cirrhosis and primary sclerosing cholangitis.Knockout of microRNA-21 reduces biliary hyperplasia and liver fibrosis in cholestatic bile duct ligated mice.The secretin/secretin receptor axis modulates liver fibrosis through changes in transforming growth factor-β1 biliary secretion in mice.The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis.Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells.Curcumin inhibits apoptosis by regulating intracellular calcium release, reactive oxygen species and mitochondrial depolarization levels in SH-SY5Y neuronal cells.Inhibition of mast cell-secreted histamine decreases biliary proliferation and fibrosis in primary sclerosing cholangitis Mdr2(-/-) mice.Curcumin Regulates Colon Cancer by Inhibiting P-Glycoprotein in In-situ Cancerous Colon Perfusion Rat Model.Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice.Curcumin attenuates high glucose-induced inflammatory injury through the reactive oxygen species-phosphoinositide 3-kinase/protein kinase B-nuclear factor-κB signaling pathway in rat thoracic aorta endothelial cells.Lack of efficacy of mTOR inhibitors and ACE pathway inhibitors as antifibrotic agents in evolving and established fibrosis in Mdr2⁻/⁻ mice.Protective Effects of Indian Spice Curcumin Against Amyloid-β in Alzheimer's Disease.Substance P increases liver fibrosis by differential changes in senescence of cholangiocytes and hepatic stellate cells.Curcumin induces ABCA1 expression and apolipoprotein A-I-mediated cholesterol transmembrane in the chronic cerebral hypoperfusion aging rats.Colesevelam attenuates cholestatic liver and bile duct injury in Mdr2-/- mice by modulating composition, signalling and excretion of faecal bile acids.MiR-873-5p acts as an epigenetic regulator in early stages of liver fibrosis and cirrhosis Effect of Curcumin and Gliotoxin on Rat Liver Myofibroblast Culture

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Curcumin improves sclerosing cholangitis in Mdr2-/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation.

http://www.wikidata.org/entity/Q37130129

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bilimsel makale

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scientific article published on April 2010

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Curcumin improves sclerosing c ...... l myofibroblast proliferation.

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Curcumin improves sclerosing c ...... l myofibroblast proliferation.

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Curcumin improves sclerosing c ...... l myofibroblast proliferation.

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Andrea Thüringer

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Anna Baghdasaryan

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Astrid Kosters

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Dagmar Silbert

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Judith Gumhold

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Katharina Leski

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Michael Trauner

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Peter Fickert

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Saul J Karpen

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Thierry Claudel

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P2860

Ursodeoxycholic acid for primary biliary cirrhosis

Direct expression cloning of vascular cell adhesion molecule 1, a cytokine-induced endothelial protein that binds to lymphocytes

Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent

The effect of curcumin and placebo on human gall-bladder function: an ultrasound study.

Effects of curcumin on peroxisome proliferator-activated receptor gamma expression and nuclear translocation/redistribution in culture-activated rat hepatic stellate cells.

Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury.

Fibrogenesis I. New insights into hepatic stellate cell activation: the simple becomes complex.

Bile salt transporters: molecular characterization, function, and regulation.

Long-term effects of mid-dose ursodeoxycholic acid in primary biliary cirrhosis: a meta-analysis of randomized controlled trials.

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521-530

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