Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents.
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KCN1, a novel synthetic sulfonamide anticancer agent: in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacologySynthesis and Biological Investigation of some Novel Sulfonamide and Amide Derivatives Containing Coumarin MoietiesBiology of advanced uveal melanoma and next steps for clinical therapeutics.Hypoxia inducible factor pathway inhibitors as anticancer therapeutics.Novel approaches to glioma drug design and drug screening.Arylsulfonamide KCN1 inhibits in vivo glioma growth and interferes with HIF signaling by disrupting HIF-1α interaction with cofactors p300/CBP.Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor.Purifying Properly Folded Cysteine-rich, Zinc Finger Containing Recombinant Proteins for Structural Drug Targeting Studies: the CH1 Domain of p300 as a Case Example.Hypoxia-inducible factor-1 (HIF-1) inhibitors from the last decade (2007 to 2016): A "structure-activity relationship" perspective.Bio-inspired benzo[k,l]xanthene lignans: synthesis, DNA-interaction and antiproliferative properties
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P2860
Design and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 24 July 2012
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Design and in vitro activities ...... ibitors and anticancer agents.
@en
Design and in vitro activities ...... ibitors and anticancer agents.
@nl
type
label
Design and in vitro activities ...... ibitors and anticancer agents.
@en
Design and in vitro activities ...... ibitors and anticancer agents.
@nl
prefLabel
Design and in vitro activities ...... ibitors and anticancer agents.
@en
Design and in vitro activities ...... ibitors and anticancer agents.
@nl
P2093
P2860
P356
P1476
Design and in vitro activities ...... ibitors and anticancer agents.
@en
P2093
Adnan Abdul Jabbar
Chalet Tan
Deborah Culver
James P Snyder
Jiyoung Mun
Mark M Goodman
Narra Sarojini Devi
Shaoman Yin
Yingzhe Wang
P2860
P304
P356
10.1021/JM300752N
P407
P577
2012-07-24T00:00:00Z