Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.
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Eph receptors and ephrin ligands: important players in angiogenesis and tumor angiogenesisA role for PP1/NIPP1 in steering migration of human cancer cellsSpatial organization of EphA2 at the cell-cell interface modulates trans-endocytosis of ephrinA1.Exploring the link between germline and somatic genetic alterations in breast carcinogenesis.An integrated genomic approach identifies persistent tumor suppressive effects of transforming growth factor-β in human breast cancerEph/ephrin profiling in human breast cancer reveals significant associations between expression level and clinical outcome.Decreased expression of receptor tyrosine kinase of EphB1 protein in renal cell carcinomas.Genome wide proteomics of ERBB2 and EGFR and other oncogenic pathways in inflammatory breast cancer.VAMP-associated protein B (VAPB) promotes breast tumor growth by modulation of Akt activity.Emerging strategies for EphA2 receptor targeting for cancer therapeutics.CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis.The receptor tyrosine kinase EphA2 is a direct target gene of hypermethylated in cancer 1 (HIC1).Clinical relevance of Ephs and ephrins in cancer: lessons from breast, colorectal, and lung cancer profiling.Advances in malignant pleural mesothelioma therapy: targeting EphA2 a novel approach.Effects of cancer-associated EPHA3 mutations on lung cancer.Increased expression of EphA1 protein in prostate cancers correlates with high Gleason score.EPH/ephrin profile and EPHB2 expression predicts patient survival in breast cancerElevation of receptor tyrosine kinase EphA2 mediates resistance to trastuzumab therapy.EphB4 tyrosine kinase stimulation inhibits growth of MDA-MB-231 breast cancer cells in a dose and time dependent manner.Roles of EphA2 in Development and Disease.The role of EPH receptors in cancer-related epithelial-mesenchymal transitionEph- and ephrin-dependent mechanisms in tumor and stem cell dynamics.The double-edged sword: conserved functions of extracellular hsp90 in wound healing and cancer.Non-HER2 signaling pathways activated in resistance to anti-HER2 therapy in breast cancer.miR-200a inhibits migration of triple-negative breast cancer cells through direct repression of the EPHA2 oncogene.EphA2 targeting pegylated nanocarrier drug delivery system for treatment of lung cancer.Asymmetry at cell-cell interfaces direct cell sorting, boundary formation, and tissue morphogenesis.Evidence for a dual function of EphB4 as tumor promoter and suppressor regulated by the absence or presence of the ephrin-B2 ligand.Research resource: New and diverse substrates for the insulin receptor isoform A revealed by quantitative proteomics after stimulation with IGF-II or insulin.Dual targeting of EphA2 and ER restores tamoxifen sensitivity in ER/EphA2-positive breast cancer.The Ephrin-A1/EPHA2 Signaling Axis Regulates Glutamine Metabolism in HER2-Positive Breast Cancer.Therapy of pancreatic cancer via an EphA2 receptor-targeted delivery of gemcitabine.High expression of EphA1 in esophageal squamous cell carcinoma is associated with lymph node metastasis and advanced disease.Aberrant EPHB4 gene methylation and childhood acute lymphoblastic leukemia.The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.EphB4: A promising target for upper aerodigestive malignancies.Increased EphB2 expression predicts cholangiocarcinoma metastasis.
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Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 22 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.
@en
Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.
@nl
type
label
Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.
@en
Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.
@nl
prefLabel
Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.
@en
Eph receptors in breast cancer: roles in tumor promotion and tumor suppression.
@nl
P2860
P921
P356
P1476
Eph receptors in breast cancer: roles in tumor promotion and tumor suppression
@en
P2093
Dana M Brantley-Sieders
P2860
P2888
P356
10.1186/BCR2207
P577
2008-12-22T00:00:00Z
P5875
P6179
1012216765