Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys. - Wikidata - awgldk - TriplyDB

Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys.

Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys.

http://www.wikidata.org/entity/Q37136853

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Regulation of MAP kinase-directed mitogenic and protein kinase B-mediated signaling by cannabinoid receptor type 1 in skeletal muscle cells Current therapies and emerging drugs in the pipeline for type 2 diabetes.Liraglutide Exerts Antidiabetic Effect via PTP1B and PI3K/Akt2 Signaling Pathway in Skeletal Muscle of KKAy Mice.Protein tyrosine phosphatase 1B inhibitors: a molecular level legitimate approach for the management of diabetes mellitus.High-fat diet-induced changes in liver thioredoxin and thioredoxin reductase as a novel feature of insulin resistance.Protein-tyrosine phosphatase 1B substrates and metabolic regulation Protein tyrosine phosphatase non-receptor type 14 is a novel sperm-motility biomarker.Fructose-fed rhesus monkeys: a nonhuman primate model of insulin resistance, metabolic syndrome, and type 2 diabetes.Effects of hepatic protein tyrosine phosphatase 1B and methionine restriction on hepatic and whole-body glucose and lipid metabolism in mice.Skeletal muscle protein tyrosine phosphatase 1B regulates insulin sensitivity in African Americans.Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation Resveratrol prevents β-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet.T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice Fish oil supplementation ameliorates fructose-induced hypertriglyceridemia and insulin resistance in adult male rhesus macaques.Protein tyrosine phosphatases as drug targets: strategies and challenges of inhibitor development.Influence of diverse chemical modifications on the ADME characteristics and toxicology of antisense oligonucleotides.Targeting hepatic glucose metabolism in the treatment of type 2 diabetes.Targeting density-enhanced phosphatase-1 (DEP-1) with antisense oligonucleotides improves the metabolic phenotype in high-fat diet-fed mice.A methodology for global-sensitivity analysis of time-dependent outputs in systems biology modelling.Use and Importance of Nonhuman Primates in Metabolic Disease Research: Current State of the Field.Novel Mixed-Type Inhibitors of Protein Tyrosine Phosphatase 1B. Kinetic and Computational Studies.

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Inhibition of protein tyrosine phosphatase-1B with antisense oligonucleotides improves insulin sensitivity and increases adiponectin concentrations in monkeys.

http://www.wikidata.org/entity/Q37136853

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 22 January 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Inhibition of protein tyrosine ...... tin concentrations in monkeys.

@en

Inhibition of protein tyrosine ...... tin concentrations in monkeys.

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type

label

Inhibition of protein tyrosine ...... tin concentrations in monkeys.

@en

Inhibition of protein tyrosine ...... tin concentrations in monkeys.

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prefLabel

Inhibition of protein tyrosine ...... tin concentrations in monkeys.

@en

Inhibition of protein tyrosine ...... tin concentrations in monkeys.

@nl

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Inhibition of protein tyrosine ...... tin concentrations in monkeys.

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Andrew A Bremer

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Arthur A Levin

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Brett P Monia

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James L Graham

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Kimber L Stanhope

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Lynnetta M Watts

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Madeline Butler

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Michael M Swarbrick

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Peter J Havel

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Robert A McKay

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P2860

Protein-tyrosine phosphatase-1B negatively regulates insulin signaling in l6 myocytes and Fao hepatoma cells

PTP1B regulates leptin signal transduction in vivo

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

Obesity is associated with macrophage accumulation in adipose tissue

Protein-tyrosine phosphatase 1B as new activator for hepatic lipogenesis via sterol regulatory element-binding protein-1 gene expression

Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene

Adiponectin and adiponectin receptors

A review of the issues in the pharmacokinetics and toxicology of phosphorothioate antisense oligonucleotides.

Protein tyrosine phosphatase-1B in diabetes.

PTP1B antisense oligonucleotide lowers PTP1B protein, normalizes blood glucose, and improves insulin sensitivity in diabetic mice.

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1670-1679

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scholarly article

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10.1210/EN.2008-0885

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150

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2009-01-22T00:00:00Z

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23933611

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19164474

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