The role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexes
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Emerging roles for the FSH receptor adapter protein APPL1 and overlap of a putative 14-3-3τ interaction domain with a canonical G-protein interaction siteUnderstanding molecular recognition by G protein βγ subunits on the path to pharmacological targetingFunction and Regulation of Heterotrimeric G Proteins during ChemotaxisTargeting Protein Kinase C Downstream of Growth Factor and Adhesion SignallingNuclear GPCRs in cardiomyocytes: an insider's view of β-adrenergic receptor signalingGα(i/o)-coupled receptor-mediated sensitization of adenylyl cyclase: 40 years laterSulfation of the FLAG epitope is affected by co-expression of G protein-coupled receptors in a mammalian cell modelCorticotropin releasing factor-induced CREB activation in striatal neurons occurs via a novel Gβγ signaling pathwayDynein light chain Tctex-type 1 modulates orexin signaling through its interaction with orexin 1 receptorThe Gβγ-Src signaling pathway regulates TNF-induced necroptosis via control of necrosome translocationKrüppel-like factor 11 regulates the expression of metabolic genes via an evolutionarily conserved protein interaction domain functionally disrupted in maturity onset diabetes of the young.Ethanol effects on glycinergic transmission: From molecular pharmacology to behavior responsesStable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling.Adenosine A2A receptor signaling and golf assembly show a specific requirement for the gamma7 subtype in the striatumSynergistic roles for G-protein γ3 and γ7 subtypes in seizure susceptibility as revealed in double knock-out mice.The Fog signaling pathway: insights into signaling in morphogenesis.The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.Silencing of odorant receptor genes by G protein βγ signaling ensures the expression of one odorant receptor per olfactory sensory neuron.Cytosolic phospholipase A2: a member of the signalling pathway of a new G protein alpha subunit in Sporothrix schenckii.Boolean modeling of transcriptome data reveals novel modes of heterotrimeric G-protein actionNMR analysis of G-protein betagamma subunit complexes reveals a dynamic G(alpha)-Gbetagamma subunit interface and multiple protein recognition modes.Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.G alpha(i) and G betagamma jointly regulate the conformations of a G betagamma effector, the neuronal G protein-activated K+ channel (GIRK)Conformational flexibility and binding interactions of the G protein βγ heterodimer.Growth inhibition of human breast carcinoma cells by overexpression of regulator of G-protein signaling 4.Interaction of the heterotrimeric G protein alpha subunit SSG-1 of Sporothrix schenckii with proteins related to stress response and fungal pathogenicity using a yeast two-hybrid assay.[EXPRESS] Peripheral inflammatory injury alters the relative abundance of Gα subunits in the dorsal horn of the spinal cord and in the rostral ventromedial medulla of male rats.Gβγ subunits inhibit Epac-induced melanoma cell migration.Regulation of constitutive cargo transport from the trans-Golgi network to plasma membrane by Golgi-localized G protein betagamma subunits.An N-terminal polybasic motif of Gαq is required for signaling and influences membrane nanodomain distribution.Fluorescent protein complementation assays: new tools to study G protein-coupled receptor oligomerization and GPCR-mediated signaling.Rational design of a selective covalent modifier of G protein βγ subunits.Purification of heterotrimeric G protein alpha subunits by GST-Ric-8 association: primary characterization of purified G alpha(olf).Location-dependent signaling of the group 1 metabotropic glutamate receptor mGlu5.HCMV pUS28 initiates pro-migratory signaling via activation of Pyk2 kinaseSignaling specificity provided by the Arabidopsis thaliana heterotrimeric G-protein γ subunits AGG1 and AGG2 is partially but not exclusively provided through transcriptional regulationThe role of G proteins in assembly and function of Kir3 inwardly rectifying potassium channels.Mono-ADP-ribosylation of the G protein betagamma dimer is modulated by hormones and inhibited by Arf6.Lighting up multiprotein complexes: lessons from GPCR oligomerizationA systems genetic analysis of alcohol drinking by mice, rats and men: influence of brain GABAergic transmission.
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The role of Gbetagamma subunits in the organization, assembly, and function of GPCR signaling complexes
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
The role of Gbetagamma subunit ...... on of GPCR signaling complexes
@en
The role of Gbetagamma subunit ...... n of GPCR signaling complexes.
@nl
type
label
The role of Gbetagamma subunit ...... on of GPCR signaling complexes
@en
The role of Gbetagamma subunit ...... n of GPCR signaling complexes.
@nl
prefLabel
The role of Gbetagamma subunit ...... on of GPCR signaling complexes
@en
The role of Gbetagamma subunit ...... n of GPCR signaling complexes.
@nl
P2093
P2860
P1476
The role of Gbetagamma subunit ...... on of GPCR signaling complexes
@en
P2093
Mélanie Robitaille
R Victor Rebois
Terence E Hébert
P2860
P356
10.1146/ANNUREV-PHARMTOX-061008-103038
P577
2009-01-01T00:00:00Z