Human-like mouse models for testing the efficacy and safety of anti-beta2-microglobulin monoclonal antibodies to treat myeloma
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Killing tumor cells through their surface beta(2)-microglobulin or major histocompatibility complex class I molecules.Novel immunotherapiesAnti-β₂M monoclonal antibodies kill myeloma cells via cell- and complement-mediated cytotoxicity.Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-myeloma activity.Targeting cell surface β2 -microglobulin by pentameric IgM antibodiesTherapeutic monoclonal antibodies for multiple myeloma: an update and future perspectives.Anti-β₂-microglobulin monoclonal antibodies overcome bortezomib resistance in multiple myeloma by inhibiting autophagy.Constitutive activation of p38 MAPK in tumor cells contributes to osteolytic bone lesions in multiple myeloma.Targeting Human β-Microglobulin with Monoclonal Antibodies in Multiple Myeloma - A Potential in Treatment.Serum beta-2 microglobulin in malignant lymphomas: an old but powerful prognostic factor.
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Human-like mouse models for testing the efficacy and safety of anti-beta2-microglobulin monoclonal antibodies to treat myeloma
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Human-like mouse models for te ...... al antibodies to treat myeloma
@en
Human-like mouse models for te ...... l antibodies to treat myeloma.
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type
label
Human-like mouse models for te ...... al antibodies to treat myeloma
@en
Human-like mouse models for te ...... l antibodies to treat myeloma.
@nl
prefLabel
Human-like mouse models for te ...... al antibodies to treat myeloma
@en
Human-like mouse models for te ...... l antibodies to treat myeloma.
@nl
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Human-like mouse models for te ...... al antibodies to treat myeloma
@en
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Jianfei Qian
Larry W Kwak
Sungyongl Hong
Yabing Cao
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10.1158/1078-0432.CCR-08-1823
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P577
2009-02-01T00:00:00Z