Molecular basis for the ATPase activity of CFTR.

Molecular basis for the ATPase activity of CFTR.

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http://www.wikidata.org/entity/Q37140103
Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutantATP and AMP mutually influence their interaction with the ATP-binding cassette (ABC) adenylate kinase cystic fibrosis transmembrane conductance regulator (CFTR) at separate binding sites.The H-loop in the second nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator is required for efficient chloride channel closingA single amino acid substitution in CFTR converts ATP to an inhibitory ligand.Mutating the Conserved Q-loop Glutamine 1291 Selectively Disrupts Adenylate Kinase-dependent Channel Gating of the ATP-binding Cassette (ABC) Adenylate Kinase Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) and Reduces Channel Function inDemonstration of phosphoryl group transfer indicates that the ATP-binding cassette (ABC) transporter cystic fibrosis transmembrane conductance regulator (CFTR) exhibits adenylate kinase activityDynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stabilityGlutathione in cancer cell deathNMR and EPR studies of membrane transporters.CFTR: A New Horizon in the Pathomechanism and Treatment of Pancreatitis.Managing cystic fibrosis: strategies that increase life expectancy and improve quality of life.Current insights into the role of PKA phosphorylation in CFTR channel activity and the pharmacological rescue of cystic fibrosis disease-causing mutants.Drug-drug plasma protein binding interactions of ivacaftor.CFTR is a mechanosensitive anion channel: a real stretch?The NBDs that wouldn't die: A cautionary tale of the use of isolated nucleotide binding domains of ABC transporters.Cystic fibrosis transmembrane conductance regulator in the gills of the climbing perch, Anabas testudineus, is involved in both hypoosmotic regulation during seawater acclimation and active ammonia excretion during ammonia exposure.Sites associated with Kalydeco binding on human Cystic Fibrosis Transmembrane Conductance Regulator revealed by Hydrogen/Deuterium Exchange.
P2860

Molecular basis for the ATPase activity of CFTR.

Item
http://www.wikidata.org/entity/Q37140103
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 April 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Molecular basis for the ATPase activity of CFTR.
@en
Molecular basis for the ATPase activity of CFTR.
@nl
type
label
Molecular basis for the ATPase activity of CFTR.
@en
Molecular basis for the ATPase activity of CFTR.
@nl
prefLabel
Molecular basis for the ATPase activity of CFTR.
@en
Molecular basis for the ATPase activity of CFTR.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P577
P698
P356
P1433
P1476
Molecular basis for the ATPase activity of CFTR.
@en
P2093
P304
P31
P356
P407
P433
P478
P577
P698