Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy
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Autophagy and endocrine resistance in breast cancerPhenethyl isothiocyanate and paclitaxel synergistically enhanced apoptosis and alpha-tubulin hyperacetylation in breast cancer cellsHigh Bak Expression Is Associated with a Favorable Prognosis in Breast Cancer and Sensitizes Breast Cancer Cells to PaclitaxelSensitization of tamoxifen-resistant breast cancer cells by Z-ligustilide through inhibiting autophagy and accumulating DNA damagesHydroxychloroquine inhibits autophagy to potentiate antiestrogen responsiveness in ER+ breast cancer.Clinical potential of novel therapeutic targets in breast cancer: CDK4/6, Src, JAK/STAT, PARP, HDAC, and PI3K/AKT/mTOR pathways.Efficacy of histone deacetylase and estrogen receptor inhibition in breast cancer cells due to concerted down regulation of AktA phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancerAutophagy: cancer's friend or foe?Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpressionVorinostat approved in Japan for treatment of cutaneous T-cell lymphomas: status and prospects.Therapeutic Implications of Cellular Heterogeneity and Plasticity in Breast CancerTargeting triple-negative breast cancer cells with the histone deacetylase inhibitor panobinostat.Randomized phase II, double-blind, placebo-controlled study of exemestane with or without entinostat in postmenopausal women with locally recurrent or metastatic estrogen receptor-positive breast cancer progressing on treatment with a nonsteroidal aHistone deacetylase 10 promotes autophagy-mediated cell survival.CSC-3436 switched tamoxifen-induced autophagy to apoptosis through the inhibition of AMPK/mTOR pathway.LSD1 engages a corepressor complex for the activation of the estrogen receptor α by estrogen and cAMPA chimeric SERM-histone deacetylase inhibitor approach to breast cancer therapy.Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy.Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy.Interplay between histone deacetylases and autophagy--from cancer therapy to neurodegeneration.miRNAs as mediators of drug resistance.Histone deacetylase inhibitors and cell death.Detection of Autophagy Induction After HDAC Inhibitor Treatment in Leukemic Cells.Diagnostic and Therapeutic Implications of Histone Epigenetic Modulators in Breast Cancer.Mechanisms of autophagy and apoptosis: Recent developments in breast cancer cells.Autophagic regulation of cell growth by altered expression of Beclin 1 in triple-negative breast cancer.Efficient new constructs against triple negative breast cancer cells: synthesis and preliminary biological study of ferrocifen-SAHA hybrids and related species.Valproic acid may exerts its cytotoxic effect through rassf1a expression induction in acute myeloid leukemia.Measurement of autophagy by flow cytometry.Use of LysoTracker dyes: a flow cytometric study of autophagy.Autologous Fat Grafting as a Novel Antiestrogen Vehicle for the Treatment of Breast Cancer.Suppression of eEF-2K-mediated autophagy enhances the cytotoxicity of Raddeanin A against human breast cancer cells in vitro.
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Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 February 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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Addition of a histone deacetyl ...... by the induction of autophagy
@en
Addition of a histone deacetyl ...... by the induction of autophagy.
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type
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Addition of a histone deacetyl ...... by the induction of autophagy
@en
Addition of a histone deacetyl ...... by the induction of autophagy.
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Addition of a histone deacetyl ...... by the induction of autophagy
@en
Addition of a histone deacetyl ...... by the induction of autophagy.
@nl
P2093
P2860
P1476
Addition of a histone deacetyl ...... by the induction of autophagy
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P2093
Douglas C Marchion
Elona Biçaku
Kenneth T Thurn
Pamela N Münster
Scott Thomas
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P2888
P304
P356
10.1007/S10549-011-1364-Y
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P577
2011-02-05T00:00:00Z