The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.
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Nano-Therapeutics for the Lung: State-of-the-Art and Future PerspectivesMucus penetrating nanoparticles: biophysical tool and method of drug and gene deliveryMucoadhesive nanoparticles may disrupt the protective human mucus barrier by altering its microstructureAdvanced Therapeutic Strategies for Chronic Lung Disease Using Nanoparticle-Based Drug DeliveryParticle tracking in drug and gene delivery research: State-of-the-art applications and methodsHighly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapyBarriers to inhaled gene therapy of obstructive lung diseases: A reviewBiomedical Applications of Biodegradable Polymers.Use of single-site-functionalized PEG dendrons to prepare gene vectors that penetrate human mucus barriersOvercoming the cystic fibrosis sputum barrier to leading adeno-associated virus gene therapy vectorsMicrostructural alterations of sputum in cystic fibrosis lung disease.Nanoparticles that do not adhere to mucus provide uniform and long-lasting drug delivery to airways following inhalation.Combinatorial synthesis with high throughput discovery of protein-resistant membrane surfacesNanoparticles reveal that human cervicovaginal mucus is riddled with pores larger than viruses.Common gene therapy viral vectors do not efficiently penetrate sputum from cystic fibrosis patients.Novel mucus-penetrating liposomes as a potential oral drug delivery system: preparation, in vitro characterization, and enhanced cellular uptakeDiscovery of low mucus adhesion surfaces.Nanotechnology approaches for inhalation treatment of fibrosis.Pretreatment of human cervicovaginal mucus with pluronic F127 enhances nanoparticle penetration without compromising mucus barrier properties to herpes simplex virusRapid transport of muco-inert nanoparticles in cystic fibrosis sputum treated with N-acetyl cysteineDrug carrier nanoparticles that penetrate human chronic rhinosinusitis mucus.Quantitative nanoparticle tracking: applications to nanomedicine.N-acetylcysteine enhances cystic fibrosis sputum penetration and airway gene transfer by highly compacted DNA nanoparticles.Highly compacted DNA nanoparticles with low MW PEG coatings: in vitro, ex vivo and in vivo evaluation.Non-degradative intracellular trafficking of highly compacted polymeric DNA nanoparticlesOral drug delivery with polymeric nanoparticles: the gastrointestinal mucus barriers.Active microrheology determines scale-dependent material properties of Chaetopterus mucus.Nanoparticle diffusion in respiratory mucus from humans without lung disease.PEGylation as a strategy for improving nanoparticle-based drug and gene deliverySurface modified poly(β amino ester)-containing nanoparticles for plasmid DNA delivery.Impact of Surface Polyethylene Glycol (PEG) Density on Biodegradable Nanoparticle Transport in Mucus ex Vivo and Distribution in Vivo.Ex vivo characterization of particle transport in mucus secretions coating freshly excised mucosal tissues.Scalable method to produce biodegradable nanoparticles that rapidly penetrate human mucusBiodegradable polymer nanoparticles that rapidly penetrate the human mucus barrier.The microstructure and bulk rheology of human cervicovaginal mucus are remarkably resistant to changes in pHLung gene therapy with highly compacted DNA nanoparticles that overcome the mucus barrier.Challenges and advances in the development of inhalable drug formulations for cystic fibrosis lung disease.Mucoadhesive nanomedicines: characterization and modulation of mucoadhesion at the nanoscale.Pseudomonas aeruginosa infection in cystic fibrosis lung disease and new perspectives of treatment: a review.Single-particle tracking for studying nanomaterial dynamics: applications and fundamentals in drug delivery.
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P2860
The penetration of fresh undiluted sputum expectorated by cystic fibrosis patients by non-adhesive polymer nanoparticles.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 26 January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
The penetration of fresh undil ...... dhesive polymer nanoparticles.
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The penetration of fresh undil ...... dhesive polymer nanoparticles.
@nl
type
label
The penetration of fresh undil ...... dhesive polymer nanoparticles.
@en
The penetration of fresh undil ...... dhesive polymer nanoparticles.
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prefLabel
The penetration of fresh undil ...... dhesive polymer nanoparticles.
@en
The penetration of fresh undil ...... dhesive polymer nanoparticles.
@nl
P2093
P2860
P921
P1433
P1476
The penetration of fresh undil ...... adhesive polymer nanoparticles
@en
P2093
Jung Soo Suk
Justin Hanes
Laura M Ensign
Samuel K Lai
Ying-Ying Wang
P2860
P304
P356
10.1016/J.BIOMATERIALS.2008.12.076
P577
2009-01-26T00:00:00Z