Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation.
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Inflammasome-mediated cell death in response to bacterial pathogens that access the host cell cytosol: lessons from legionella pneumophilaCellular Aspects of Shigella Pathogenesis: Focus on the Manipulation of Host Cell ProcessesConverging roles of caspases in inflammasome activation, cell death and innate immunityThe NAIP/NLRC4 inflammasomesInflammasomes: mechanism of action, role in disease, and therapeuticsMechanisms of inflammasome activation: recent advances and novel insightsPyroptotic cell death defends against intracellular pathogensThe cell biology of inflammasomes: Mechanisms of inflammasome activation and regulationModulation of the Inflammasome Signaling Pathway by Enteropathogenic and Enterohemorrhagic Escherichia coliInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseBacterial recognition pathways that lead to inflammasome activationModulation of the host innate immune and inflammatory response by translocated bacterial proteinsEnteropathogenic Escherichia coli Uses NleA to Inhibit NLRP3 Inflammasome ActivationActin polymerization as a key innate immune effector mechanism to control Salmonella infectionMacrophages mediate flagellin induced inflammasome activation and host defense in zebrafishThe Tick Protein Sialostatin L2 Binds to Annexin A2 and Inhibits NLRC4-Mediated Inflammasome Activation.Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.Detection of cytosolic bacteria by inflammatory caspases.Inflammasomes in host response to protozoan parasites.Distinct contributions of interleukin-1α (IL-1α) and IL-1β to innate immune recognition of Pseudomonas aeruginosa in the lung.Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages.An inherited mutation in NLRC4 causes autoinflammation in human and mice.Inflammasomes as polyvalent cell death platforms.Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5Inflammasome activation in response to the Yersinia type III secretion system requires hyperinjection of translocon proteins YopB and YopD.Sensing cytosolic RpsL by macrophages induces lysosomal cell death and termination of bacterial infectionEpithelial NAIPs protect against colonic tumorigenesis.NLRC4 and TLR5 each contribute to host defense in respiratory melioidosis.Regulation of inflammasome activation.Secretion of Flagellar Proteins by the Pseudomonas aeruginosa Type III Secretion-Injectisome SystemMitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.Cutting Edge: Inflammasome Activation in Primary Human Macrophages Is Dependent on FlagellinMechanisms and pathways of innate immune activation and regulation in health and cancer.Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.Bacterial internalization is required to trigger NIK-dependent NF-κB activation in response to the bacterial type three secretion system.Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium.Innate Immune Signaling Activated by MDR Bacteria in the AirwayA single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assemblyNAIP proteins are required for cytosolic detection of specific bacterial ligands in vivo.
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Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 12 August 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Human NAIP and mouse NAIP1 rec ...... n for inflammasome activation.
@en
Human NAIP and mouse NAIP1 rec ...... n for inflammasome activation.
@nl
type
label
Human NAIP and mouse NAIP1 rec ...... n for inflammasome activation.
@en
Human NAIP and mouse NAIP1 rec ...... n for inflammasome activation.
@nl
prefLabel
Human NAIP and mouse NAIP1 rec ...... n for inflammasome activation.
@en
Human NAIP and mouse NAIP1 rec ...... n for inflammasome activation.
@nl
P2093
P2860
P356
P1476
Human NAIP and mouse NAIP1 rec ...... n for inflammasome activation.
@en
P2093
Jianjin Shi
Jieling Yang
P2860
P304
14408-14413
P356
10.1073/PNAS.1306376110
P407
P577
2013-08-12T00:00:00Z