about
Regulatory Principles Governing Tissue Specificity of Developmental EnhancersEvolution of New cis-Regulatory Motifs Required for Cell-Specific Gene Expression in CaenorhabditisThe appeasement of Doug: a synthetic approach to enhancer biology.Enhancers and chromatin structures: regulatory hubs in gene expression and diseases.The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6.Reprogramming cell fate with a genome-scale library of artificial transcription factors.Genome-wide mapping of autonomous promoter activity in human cellsTo Be Specific or Not: The Critical Relationship Between Hox And TALE Proteins.An ancient yet flexible cis-regulatory architecture allows localized Hedgehog tuning by patched/Ptch1.Syntax compensates for poor binding sites to encode tissue specificity of developmental enhancersStepwise Progression of Embryonic PatterningCoupled enhancer and coding sequence evolution of a homeobox gene shaped leaf diversity.Transcription factor family-specific DNA shape readout revealed by quantitative specificity models.Measuring time during early embryonic development.Identification and Function of Enhancers in the Human Genome.High constitutive activity of a broad panel of housekeeping and tissue-specific cis-regulatory elements depends on a subset of ETS proteinsEver-Changing Landscapes: Transcriptional Enhancers in Development and Evolution.Nuclear Receptor Function through Genomics: Lessons from the Glucocorticoid Receptor.Enhancer evolution and the origins of morphological novelty.Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer.How to tune an enhancer.Interplay of cis and trans mechanisms driving transcription factor binding and gene expression evolution.Impact of regulatory variation across human iPSCs and differentiated cells.Nuclear microenvironments modulate transcription from low-affinity enhancers.Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cells.Natural variation in stochastic photoreceptor specification and color preference in Drosophila.Local sequence features that influence AP-1 cis-regulatory activity.HOXA1 and TALE proteins display cross-regulatory interactions and form a combinatorial binding code on HOXA1 targets.An FGF-driven feed-forward circuit patterns the cardiopharyngeal mesoderm in space and time.Capicua controls Toll/IL-1 signaling targets independently of RTK regulation.Dynamic changes in Sox2 spatio-temporal expression promote the second cell fate decision through Fgf4/Fgfr2 signalling in preimplantation mouse embryos.Assessing sufficiency and necessity of enhancer activities for gene expression and the mechanisms of transcription activation.Degenerate Pax2 and Senseless binding motifs improve detection of low-affinity sites required for enhancer specificity.A CRISPR view of gene regulation.Accurate and sensitive quantification of protein-DNA binding affinity.MMARGE: Motif Mutation Analysis for Regulatory Genomic ElementsIntrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites
P2860
Q27013802-25BB4590-FF73-4A6A-80C4-9128723D7BFAQ27308019-072BDB48-A4AB-47F9-992B-F7043293E4FBQ30385188-873C9FA2-6489-4A59-A040-7472EA6F93DAQ33613467-35748597-8BAC-4473-ACBB-4B5ECCAE1252Q36213375-638DCE97-F3BB-4895-B6BF-CD6367094FD1Q36215800-EC6CDCCF-D135-41F6-8DB5-050325DF0F4AQ36233375-275B40C6-0404-4CE4-B926-9C27D0D811F2Q36923531-8B68C64E-872B-44E1-B16F-87D18DEAFEDFQ36951875-96EF2CB9-720B-45A0-B471-3F205C3B9ED6Q37183697-72C6ACDC-8A58-427E-A40F-FD1886B07A8DQ37341006-7B673DC2-479B-4F2A-8D65-47AB3581F24BQ37461443-9E1D8E71-815B-477B-BF78-A7100D4AE411Q37668785-21455062-7D9C-486C-9F99-36839D32E69EQ38781473-40A04BCC-EA1E-4824-B4F3-9177F90C9686Q38893481-900F1F64-6296-4FDD-83E3-9EDBC2B36D53Q38919756-AF2B7097-509E-408E-94C3-E9152CF2267AQ39013266-5A60E7B4-1E1A-4D7F-A8C2-39660D4CB065Q39299559-1870C532-0EAE-47F4-A592-317BE56E0EC5Q39319871-CB881430-58E4-4B27-8BBA-8AD93FC5B406Q41621328-AD0B1C20-45E6-47C0-B423-28D626AD749CQ42350187-A82A17F4-1D75-40FD-8089-1F761212549EQ42645962-8087B300-442E-4F36-9A01-311A78DAA51EQ45990501-4AB5CA25-8991-4880-B71F-F8F9A3E64872Q46371048-486094AC-DB97-429C-A06B-D2EE7CDA1808Q46686884-971935D2-1726-415D-BC99-440C9CD34E1CQ47096553-F0049BF2-3B27-48C7-8E59-3D5A5905928CQ47203571-ECAAC435-700C-46B6-87F1-58D983ADFCFEQ47981433-A271D3D8-1B33-45F6-A8D3-E8D1CE16C311Q49240917-0D66F79A-E819-4817-A4D1-E5B49D0329A5Q50063660-B7DA95DC-5BAD-4F64-8EDC-12BDB595212AQ50421637-9F2A1264-218A-4794-A166-68A462BB2CBAQ52430543-41316042-8A24-4180-AB38-07D0B6E58BA0Q52721715-B8EFCF0A-802C-4C15-B2E3-3924A599AA6BQ55031485-4B948666-88E9-4026-BEA8-96145108CA7AQ55179536-7ECFB973-309C-48F4-9347-229BDE553979Q56475859-8D4B4FD3-70EC-4DEF-BB88-A27CDDC0F763Q58697129-331E1410-9CA4-4D8E-B749-F93A3133AD48
P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2015
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Suboptimization of developmental enhancers
@en
Suboptimization of developmental enhancers.
@nl
type
label
Suboptimization of developmental enhancers
@en
Suboptimization of developmental enhancers.
@nl
prefLabel
Suboptimization of developmental enhancers
@en
Suboptimization of developmental enhancers.
@nl
P2093
P2860
P50
P356
P1433
P1476
Suboptimization of developmental enhancers
@en
P2093
Alexander J Brandt
Katrina M Olson
Michael S Levine
P2860
P304
P356
10.1126/SCIENCE.AAC6948
P407
P577
2015-10-01T00:00:00Z