Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells. - Wikidata - awgldk - TriplyDB

Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells.

Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells.

http://www.wikidata.org/entity/Q37147482

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Myeloid-Derived Suppressor Cells in Bacterial Infections Current status of immunotherapy The potential of radiotherapy to enhance the efficacy of renal cell carcinoma therapy Signaling Circuits and Regulation of Immune Suppression by Ovarian Tumor-Associated Macrophages Myeloid-Derived Suppressor Cells: Critical Cells Driving Immune Suppression in the Tumor Microenvironment Dendritic cell vaccination, immune regulation, and clinical outcomes in ovarian cancer Hampering immune suppressors: therapeutic targeting of myeloid-derived suppressor cells in cancer Control of the immune response by pro-angiogenic factors Multimodality treatment of brain metastases from renal cell carcinoma in the era of targeted therapy Myeloid-derived cells are key targets of tumor immunotherapy Modification of the tumor microenvironment as a novel target of renal cell carcinoma therapeutics Coordinated regulation of myeloid cells by tumours The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model Prodrug AST-003 Improves the Therapeutic Index of the Multi-Targeted Tyrosine Kinase Inhibitor Sunitinib STATs in cancer inflammation and immunity: a leading role for STAT3 Reduced immunosuppressive properties of axitinib in comparison with other tyrosine kinase inhibitors.Myeloid-derived suppressor cells: the dark knight or the joker in viral infections?Breaking through a plateau in renal cell carcinoma therapeutics: development and incorporation of biomarkers Structurally modified curcumin analogs inhibit STAT3 phosphorylation and promote apoptosis of human renal cell carcinoma and melanoma cell lines.Arsenic trioxide inhibits tumor-induced myeloid-derived suppressor cells and enhances T-cell activity.Signal integration and gene induction by a functionally distinct STAT3 phosphoform.Extracerebral metastases determine the outcome of patients with brain metastases from renal cell carcinoma.Regulation of macrophage arginase expression and tumor growth by the Ron receptor tyrosine kinase Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer.Association of toxicity of sorafenib and sunitinib for human keratinocytes with inhibition of signal transduction and activator of transcription 3 (STAT3)Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2.Interleukin-6 in bone metastasis and cancer progression.Targeting immune suppressing myeloid-derived suppressor cells in oncology.STAT3 activation in monocytes accelerates liver cancer progression.Granulocyte macrophage colony-stimulating factor as a predictor of the response of metastatic renal cell carcinoma to tyrosine kinase inhibitor therapy.Intravital imaging of anti-tumor immune response and the tumor microenvironment.The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA.Targeting STAT3 in adoptively transferred T cells promotes their in vivo expansion and antitumor effects.Targeting Stat3 in the myeloid compartment drastically improves the in vivo antitumor functions of adoptively transferred T cells.Signal transducer and activator of transcription 3 in liver diseases: a novel therapeutic target.Deciphering the anticancer mechanisms of sunitinib.MDSC as a mechanism of tumor escape from sunitinib mediated anti-angiogenic therapy.Sunitinib facilitates the activation and recruitment of therapeutic anti-tumor immunity in concert with specific vaccination.Icaritin inhibits JAK/STAT3 signaling and growth of renal cell carcinoma.A pilot study of autologous tumor lysate-loaded dendritic cell vaccination combined with sunitinib for metastatic renal cell carcinoma.

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Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells.

http://www.wikidata.org/entity/Q37147482

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 24 February 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Sunitinib inhibition of Stat3 ...... duces immunosuppressive cells.

@en

Sunitinib inhibition of Stat3 ...... duces immunosuppressive cells.

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type

label

Sunitinib inhibition of Stat3 ...... duces immunosuppressive cells.

@en

Sunitinib inhibition of Stat3 ...... duces immunosuppressive cells.

@nl

prefLabel

Sunitinib inhibition of Stat3 ...... duces immunosuppressive cells.

@en

Sunitinib inhibition of Stat3 ...... duces immunosuppressive cells.

@nl

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0008-5472.CAN-08-4323

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Cancer Research

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Sunitinib inhibition of Stat3 ...... duces immunosuppressive cells.

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Andreas Herrmann

http://www.w3.org/2001/XMLSchema#string

Chunyan Zhang

http://www.w3.org/2001/XMLSchema#string

Hong Xin

http://www.w3.org/2001/XMLSchema#string

Hua Yu

http://www.w3.org/2001/XMLSchema#string

Robert Figlin

http://www.w3.org/2001/XMLSchema#string

Yan Du

http://www.w3.org/2001/XMLSchema#string

P2860

HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas

Sunitinib versus interferon alfa in metastatic renal-cell carcinoma

The von Hippel-Lindau tumor suppressor gene and kidney cancer

Stat3 mediates myeloid cell-dependent tumor angiogenesis in mice

The STATs of cancer--new molecular targets come of age

Stat3 as an oncogene

Stat3 activation is required for cellular transformation by v-src.

Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma.

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2506-2513

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scholarly article

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10.1158/0008-5472.CAN-08-4323

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6

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69

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2009-02-24T00:00:00Z

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24041383

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19244102

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apoptotic process

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2664264

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