Core principles of intramembrane proteolysis: comparison of rhomboid and site-2 family proteases
about
The roles of intramembrane proteases in protozoan parasitesMaking the cut: central roles of intramembrane proteolysis in pathogenic microorganismsCleavage of RseA by RseP requires a carboxyl-terminal hydrophobic amino acid following DegS cleavageCREST--a large and diverse superfamily of putative transmembrane hydrolases.An internal water-retention site in the rhomboid intramembrane protease GlpG ensures catalytic efficiency.Cryoelectron microscopy structure of purified gamma-secretase at 12 A resolution.Taking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysisThree-dimensional structure of the signal peptide peptidaseExpansion of type II CAAX proteases reveals evolutionary origin of γ-secretase subunit APH-1Features of Pro-σK important for cleavage by SpoIVFB, an intramembrane metalloprotease.Toward structural elucidation of the gamma-secretase complex.Biochemical and structural insights into intramembrane metalloprotease mechanisms.Residues in conserved loops of intramembrane metalloprotease SpoIVFB interact with residues near the cleavage site in pro-σKThe role of protease activity in ErbB biology.Structure and mechanism of intramembrane protease.Intramembrane proteolytic cleavage of a membrane-tethered transcription factor by a metalloprotease depends on ATP.The PARL family of mitochondrial rhomboid proteases.New insights into S2P signaling cascades: regulation, variation, and conservation.Intramembrane proteolysis in regulated protein trafficking.In vivo analysis reveals substrate-gating mutants of a rhomboid intramembrane protease display increased activity in living cells.A Golgi rhomboid protease Rbd2 recruits Cdc48 to cleave yeast SREBP.
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P2860
Core principles of intramembrane proteolysis: comparison of rhomboid and site-2 family proteases
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 26 April 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Core principles of intramembra ...... id and site-2 family proteases
@en
Core principles of intramembra ...... d and site-2 family proteases.
@nl
type
label
Core principles of intramembra ...... id and site-2 family proteases
@en
Core principles of intramembra ...... d and site-2 family proteases.
@nl
prefLabel
Core principles of intramembra ...... id and site-2 family proteases
@en
Core principles of intramembra ...... d and site-2 family proteases.
@nl
P2860
P1476
Core principles of intramembra ...... id and site-2 family proteases
@en
P2093
Sinisa Urban
Yigong Shi
P2860
P304
P356
10.1016/J.SBI.2008.03.005
P577
2008-04-26T00:00:00Z