Brucella TIR Domain-containing Protein Mimics Properties of the Toll-like Receptor Adaptor Protein TIRAP.
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Unifying themes in microbial associations with animal and plant hosts described using the gene ontologyEstablishment of Chronic Infection: Brucella's Stealth StrategySubverting Toll-Like Receptor Signaling by Bacterial PathogensType IV secretion system of Brucella spp. and its effectorsA TIR domain protein from E. faecalis attenuates MyD88-mediated signaling and NF-κB activationMolecular Mimicry in Innate Immunity: CRYSTAL STRUCTURE OF A BACTERIAL TIR DOMAINMolecular mechanisms for the subversion of MyD88 signaling by TcpC from virulent uropathogenic Escherichia coliMechanism of Bacterial Interference with TLR4 Signaling by Brucella Toll/Interleukin-1 Receptor Domain-containing Protein TcpBCrystal Structures of the Toll/Interleukin-1 Receptor (TIR) Domains from the Brucella Protein TcpB and Host Adaptor TIRAP Reveal Mechanisms of Molecular MimicryStructure of the Toll/interleukin 1 receptor (TIR) domain of the immunosuppressive Brucella effector BtpA/Btp1/TcpBThe Brucella TIR-like protein TcpB interacts with the death domain of MyD88Subversion of innate immune signaling through molecular mimicryBrucella induces an unfolded protein response via TcpB that supports intracellular replication in macrophagesInnate immune recognition of flagellin limits systemic persistence of BrucellaInhibition of TIR domain signaling by TcpC: MyD88-dependent and independent effects on Escherichia coli virulence.A Pseudomonas aeruginosa TIR effector mediates immune evasion by targeting UBAP1 and TLR adaptors.The TIR Domain Containing Locus of Enterococcus faecalis Is Predominant among Urinary Tract Infection Isolates and Downregulates Host Inflammatory Response.Immunization of mice with recombinant protein CobB or AsnC confers protection against Brucella abortus infection.Active evasion of CTL mediated killing and low quality responding CD8+ T cells contribute to persistence of brucellosis.A Staphylococcus aureus TIR domain protein virulence factor blocks TLR2-mediated NF-κB signaling.Two TIR-like domain containing proteins in a newly emerging zoonotic Staphylococcus aureus strain sequence type 398 are potential virulence factors by impacting on the host innate immune responseNoninvasive biophotonic imaging for studies of infectious disease.TIR domain-containing adaptor SARM is a late addition to the ongoing microbe-host dialog.Microbial strategies for antagonizing Toll-like-receptor signal transduction.Pathogenesis and immunobiology of brucellosis: review of Brucella-host interactionsBacillus anthracis TIR Domain-Containing Protein Localises to Cellular Microtubule Structures and Induces Autophagy.Toll/interleukin-1 receptor domain dimers as the platform for activation and enhanced inhibition of Toll-like receptor signaling.Repression of bacterial lipoprotein production by Francisella novicida facilitates evasion of innate immune recognitionCD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection.Modulation of microtubule dynamics by a TIR domain protein from the intracellular pathogen Brucella melitensis.A Comparative Analysis of the Mechanism of Toll-Like Receptor-Disruption by TIR-Containing Protein C from Uropathogenic Escherichia coli.Modulation of host microtubule dynamics by pathogenic bacteria.BtpB, a novel Brucella TIR-containing effector protein with immune modulatory functions.Bartonella and Brucella--weapons and strategies for stealth attack.Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of the TIR domain from the Brucella melitensis TIR-domain-containing protein TcpB.Survival of the fittest: how Brucella strains adapt to their intracellular niche in the host.The role of NLRP3 and AIM2 in inflammasome activation during Brucella abortus infection.Comparative phylogenomics and evolution of the Brucellae reveal a path to virulence.An evolutionary strategy for a stealthy intracellular Brucella pathogen.Confronting the barriers to develop novel vaccines against brucellosis.
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P2860
Brucella TIR Domain-containing Protein Mimics Properties of the Toll-like Receptor Adaptor Protein TIRAP.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 05 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Brucella TIR Domain-containing ...... eceptor Adaptor Protein TIRAP.
@en
Brucella TIR Domain-containing ...... eceptor Adaptor Protein TIRAP.
@nl
type
label
Brucella TIR Domain-containing ...... eceptor Adaptor Protein TIRAP.
@en
Brucella TIR Domain-containing ...... eceptor Adaptor Protein TIRAP.
@nl
prefLabel
Brucella TIR Domain-containing ...... eceptor Adaptor Protein TIRAP.
@en
Brucella TIR Domain-containing ...... eceptor Adaptor Protein TIRAP.
@nl
P2093
P2860
P356
P1476
Brucella TIR Domain-containing ...... eceptor Adaptor Protein TIRAP.
@en
P2093
Gary A Splitter
Girish K Radhakrishnan
Jerome S Harms
P2860
P304
P356
10.1074/JBC.M805458200
P407
P577
2009-02-05T00:00:00Z