DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity
about
New factors in mammalian DNA repair-the chromatin connection.The HTLV-1 basic leucine zipper factor (HBZ) attenuates repair of double-stranded DNA breaks via non-homologous end joining (NHEJ).Poly(ADP-ribose) Polymerase 1, PARP1, modifies EZH2 and inhibits EZH2 histone methyltransferase activity after DNA damage.
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DNA-PK-mediated phosphorylation of EZH2 regulates the DNA damage-induced apoptosis to maintain T-cell genomic integrity
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 28 July 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
DNA-PK-mediated phosphorylatio ...... ntain T-cell genomic integrity
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DNA-PK-mediated phosphorylatio ...... tain T-cell genomic integrity.
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type
label
DNA-PK-mediated phosphorylatio ...... ntain T-cell genomic integrity
@en
DNA-PK-mediated phosphorylatio ...... tain T-cell genomic integrity.
@nl
prefLabel
DNA-PK-mediated phosphorylatio ...... ntain T-cell genomic integrity
@en
DNA-PK-mediated phosphorylatio ...... tain T-cell genomic integrity.
@nl
P2093
P2860
P356
P1476
DNA-PK-mediated phosphorylatio ...... ntain T-cell genomic integrity
@en
P2093
P2860
P356
10.1038/CDDIS.2016.198
P577
2016-07-28T00:00:00Z