Precursor-product discrimination by La protein during tRNA metabolism.
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The La-Related Proteins, a Family with Connections to CancerA methods review on use of nonsense suppression to study 3' end formation and other aspects of tRNA biogenesisLa-Related Protein 4 Binds Poly(A), Interacts with the Poly(A)-Binding Protein MLLE Domain via a Variant PAM2w Motif, and Can Promote mRNA StabilityStructural Basis for Telomerase RNA Recognition and RNP Assembly by the Holoenzyme La Family Protein p65Conserved and divergent features of the structure and function of La and La-related proteins (LARPs)tRNA biology charges to the frontFunctional conservation of tRNase ZL among Saccharomyces cerevisiae, Schizosaccharomyces pombe and humans.An intrinsically disordered C terminus allows the La protein to assist the biogenesis of diverse noncoding RNA precursorsSynergic interplay of the La motif, RRM1 and the interdomain linker of LARP6 in the recognition of collagen mRNA expands the RNA binding repertoire of the La module.Novel RNA chaperone domain of RNA-binding protein La is regulated by AKT phosphorylation3' processing of eukaryotic precursor tRNAs.Comparative whole genome sequencing reveals phenotypic tRNA gene duplication in spontaneous Schizosaccharomyces pombe La mutants.Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1pAnalysis of the interaction with the hepatitis C virus mRNA reveals an alternative mode of RNA recognition by the human La proteinThe association of a La module with the PABP-interacting motif PAM2 is a recurrent evolutionary process that led to the neofunctionalization of La-related proteins.RNA polymerase III mutants in TFIIFα-like C37 that cause terminator readthrough with no decrease in transcription output.Conservation of RNA chaperone activity of the human La-related proteins 4, 6 and 7Targeted deletion of the gene encoding the La autoantigen (Sjögren's syndrome antigen B) in B cells or the frontal brain causes extensive tissue loss.Factors That Shape Eukaryotic tRNAomes: Processing, Modification and Anticodon-Codon Use.xRRM: a new class of RRM found in the telomerase La family protein p65.RNA chaperone activity of human La protein is mediated by variant RNA recognition motifEvolving specificity of tRNA 3-methyl-cytidine-32 (m3C32) modification: a subset of tRNAsSer requires N6-isopentenylation of A37.La Deletion from Mouse Brain Alters Pre-tRNA Metabolism and Accumulation of Pre-5.8S rRNA, with Neuron Death and Reactive Astrocytosis.The RNA chaperone La promotes pre-tRNA maturation via indiscriminate binding of both native and misfolded targets.SUMO Modification of the RNA-Binding Protein La Regulates Cell Proliferation and STAT3 Protein Stability.Characterizing Expression and Processing of Precursor and Mature Human tRNAs by Hydro-tRNAseq and PAR-CLIP.The La and related RNA-binding proteins (LARPs): structures, functions, and evolving perspectives.Human La binds mRNAs through contacts to the poly(A) tail.
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Precursor-product discrimination by La protein during tRNA metabolism.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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name
Precursor-product discrimination by La protein during tRNA metabolism.
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Precursor-product discrimination by La protein during tRNA metabolism.
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type
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Precursor-product discrimination by La protein during tRNA metabolism.
@en
Precursor-product discrimination by La protein during tRNA metabolism.
@nl
prefLabel
Precursor-product discrimination by La protein during tRNA metabolism.
@en
Precursor-product discrimination by La protein during tRNA metabolism.
@nl
P2860
P356
P1476
Precursor-product discrimination by La protein during tRNA metabolism
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P2093
Mark A Bayfield
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P2888
P304
P356
10.1038/NSMB.1573
P577
2009-03-15T00:00:00Z