NF-kappaB signaling regulates functional expression of the MHC class I-related neonatal Fc receptor for IgG via intronic binding sequences.
about
Unraveling the Interaction between FcRn and Albumin: Opportunities for Design of Albumin-Based TherapeuticsLymphatic delivery of etanercept via nanotopography improves response to collagen-induced arthritis.FcRn receptor-mediated pharmacokinetics of therapeutic IgG in the eye.Sp1 regulates chromatin looping between an intronic enhancer and distal promoter of the human heme oxygenase-1 gene in renal cells.On the perplexingly low rate of transport of IgG2 across the human placenta.Neonatal Fc receptor: from immunity to therapeuticsNF-κB- and AP-1-mediated DNA looping regulates osteopontin transcription in endotoxin-stimulated murine macrophages.FcRn overexpression in mice results in potent humoral response against weakly immunogenic antigen.Recent advances using FcRn overexpression in transgenic animals to overcome impediments of standard antibody technologies to improve the generation of specific antibodies.FcRn: The Architect Behind the Immune and Nonimmune Functions of IgG and Albumin.Analysis of Response Elements Involved in the Regulation of the Human Neonatal Fc Receptor Gene (FCGRT).Effect of Type 2 Diabetes Mellitus and Diabetic Nephropathy on IgG Pharmacokinetics and Subcutaneous Bioavailability in the RatOverexpression of Bovine FcRn in Mice Enhances T-Dependent Immune Responses by Amplifying T Helper Cell Frequency and Germinal Center Enlargement in the Spleen.Identification and characterization of an alternatively spliced variant of the MHC class I-related porcine neonatal Fc receptor for IgGAntibodies and their receptors: different potential roles in mucosal defense.The MHC class II-associated invariant chain interacts with the neonatal Fc gamma receptor and modulates its trafficking to endosomal/lysosomal compartments.Activation of the JAK/STAT-1 signaling pathway by IFN-gamma can down-regulate functional expression of the MHC class I-related neonatal Fc receptor for IgG.TGEV infection up-regulates FcRn expression via activation of NF-κB signaling.NF-kappaB regulates thrombin-induced ICAM-1 gene expression in cooperation with NFAT by binding to the intronic NF-kappaB site in the ICAM-1 gene.NFκB induces overexpression of bovine FcRn: a novel mechanism that further contributes to the enhanced immune response in genetically modified animals carrying extra copies of FcRn.Chapter 4: Multitasking by exploitation of intracellular transport functions the many faces of FcRn.The neonatal Fc receptor as therapeutic target in IgG-mediated autoimmune diseases.Molecular mechanisms of T-cell tolerance.Pharmacokinetics, pharmacodynamics and physiologically-based pharmacokinetic modelling of monoclonal antibodies.Tailoring anti-TNF therapy in IBD: drug levels and disease activity.Accelerating antibody discovery using transgenic animals overexpressing the neonatal Fc receptor as a result of augmented humoral immunity.The Neonatal Fc Receptor and Complement Fixation Facilitate Prophylactic Vaccine-Mediated Humoral Protection against Viral Infection in the Ocular Mucosa.Direct demonstration of a neonatal Fc receptor (FcRn)-driven endosomal sorting pathway for cellular recycling of albumin.Regulation of IL-8 promoter activity by verrucarin A in human monocytic THP-1 cells.Transepithelial transport of Fc-targeted nanoparticles by the neonatal fc receptor for oral deliveryNeonatal Fc receptor promoter gene polymorphism does not predict pharmacokinetics of IVIg or the clinical course of GBS.Neonatal Fc receptor (FcRn) and maternal-to-newborn IgE absorptionExpression of neonatal Fc receptor in the eye.Effects of fermented soybean meal on innate immunity-related gene expressions in nursery pigs acutely challenged with lipopolysaccharides.Regulation of the Human Fc-Neonatal Receptor alpha-Chain Gene FCGRT by MicroRNA-3181.
P2860
Q27027238-5992AC6E-1C81-44C5-B15B-5ADDE0ECA9BAQ30854312-FD9A4B0B-F972-4C12-B5CE-01C26189CE35Q33519532-3F46572E-FEB4-4CA7-ACA5-8C9D1CC7EEDDQ33883143-752226C8-7153-4858-A482-316FBF144777Q34253508-F5A90259-5CE6-47FF-A06A-A1FBC6E19F7BQ34268801-955AD700-D56B-4E41-A5D3-C926C21457F3Q34488498-D76A5FE1-DC38-414C-A3A5-ECBC58A62ADCQ34974778-98CA8AE6-637F-4F50-AB49-8A50058D9211Q35578023-AE6034DD-0379-4DCA-9D68-F162965691AEQ35670904-ECD289A8-6B0E-443E-A343-6A967EA45F1CQ35740089-6490D2BE-8D3A-4D5E-B114-7BB400DD359BQ35768430-0A201CB8-D969-4912-9A75-A5529167E293Q35866344-C78E1BDF-2776-4AB5-B5E4-522231D4446BQ36766511-A64E63AB-2634-42EC-94EB-767A3188F380Q37015487-F729F5AD-2D0A-4958-BA54-F7ACEDA7A1A1Q37153912-595F61A2-B02C-4E40-9BDF-25A04ACC466EQ37153929-2967D8E4-1B75-4E30-A736-2BB6CF9A9BA3Q37198590-0710B07E-2F97-4917-8A46-CCA29D033EF7Q37226874-4B2CC11C-2F68-4BA1-8BB1-5639FB8A2D0FQ37496557-8A866FA2-F50C-4852-A4B4-7D6802A8543CQ37597698-CBA34C99-F455-4562-BB77-033402BF0786Q37706192-485B648F-245D-4F1D-BFB3-8624AD7C4305Q37864696-9583AA34-8E59-498A-B2BE-A5E4F7C7478BQ38072598-C491099E-8C57-462F-9CD9-A2CC064CA01DQ38176154-AC723D4E-863B-41D5-A0A7-47FD222DC368Q38615389-32015336-D2CC-41FB-96A7-DDF82C6C0449Q38650844-FFAE4515-7156-4452-8DB7-9DB707057EDBQ38699470-F53C43F6-34DD-4A91-847B-D68DCEE8ADF8Q38966437-3741F9C6-F5E8-4057-82AE-2492A9055385Q39681409-138E8BC8-50E1-4821-8605-DD1340DE54C1Q42155763-513CE02E-2F80-488F-B830-1C3C0876AB0BQ42529967-B63AE535-D0A4-42F3-B0E9-4B233421CE9BQ42587613-228871B4-1DA4-409D-9873-61F2359A6DE4Q44876431-3570E774-1668-4E8F-8D9A-5E25C7CD4BB9Q47207165-3F78FCC2-E8A6-4DF8-A2F5-7D70647E02BE
P2860
NF-kappaB signaling regulates functional expression of the MHC class I-related neonatal Fc receptor for IgG via intronic binding sequences.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
NF-kappaB signaling regulates ...... ia intronic binding sequences.
@en
NF-kappaB signaling regulates ...... ia intronic binding sequences.
@nl
type
label
NF-kappaB signaling regulates ...... ia intronic binding sequences.
@en
NF-kappaB signaling regulates ...... ia intronic binding sequences.
@nl
prefLabel
NF-kappaB signaling regulates ...... ia intronic binding sequences.
@en
NF-kappaB signaling regulates ...... ia intronic binding sequences.
@nl
P2093
P2860
P1476
NF-kappaB signaling regulates ...... via intronic binding sequences
@en
P2093
Derry C Roopenian
Gregory J Christianson
Jun-Qi Yang
Xiaoping Zhu
P2860
P304
P356
10.4049/JIMMUNOL.179.5.2999
P407
P577
2007-09-01T00:00:00Z