An experimental and theoretical evaluation of the influence of pretargeting antibody on the tumor accumulation of effector
about
Affinity enhancement pretargeting: synthesis and testing of a 99mTc-labeled bivalent MORFTumor pretargeting in mice using MORF conjugated CC49 antibody and radiolabeled complimentary cMORF effector.Adding a clearing agent to pretargeting does not lower the tumor accumulation of the effector as predicted.A preclinical 188Re tumor therapeutic investigation using MORF/cMORF pretargeting and an antiTAG-72 antibody CC49.A semiempirical model of tumor pretargeting.The ratio of maximum percent tumour accumulations of the pretargeting agent and the radiolabelled effector is independent of tumour size.Pretargeted molecular imaging and radioimmunotherapy.Bioorthogonal chemistry: implications for pretargeted nuclear (PET/SPECT) imaging and therapy.Rules of thumb for maximum percent tumor accumulationUse of Morpholino Oligomers for Pretargeting.
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An experimental and theoretical evaluation of the influence of pretargeting antibody on the tumor accumulation of effector
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on May 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
An experimental and theoretica ...... tumor accumulation of effector
@en
An experimental and theoretica ...... umor accumulation of effector.
@nl
type
label
An experimental and theoretica ...... tumor accumulation of effector
@en
An experimental and theoretica ...... umor accumulation of effector.
@nl
prefLabel
An experimental and theoretica ...... tumor accumulation of effector
@en
An experimental and theoretica ...... umor accumulation of effector.
@nl
P2093
P2860
P1476
An experimental and theoretica ...... tumor accumulation of effector
@en
P2093
Donald J Hnatowich
Guozheng Liu
Mary Rusckowski
Shuping Dou
P2860
P304
P356
10.1158/1535-7163.MCT-07-2203
P577
2008-05-01T00:00:00Z