Chronic pharmacological and safety evaluation of Hematide, a PEGylated peptidic erythropoiesis-stimulating agent, in rodents. - Wikidata - awgldk - TriplyDB

Chronic pharmacological and safety evaluation of Hematide, a PEGylated peptidic erythropoiesis-stimulating agent, in rodents.

Chronic pharmacological and safety evaluation of Hematide, a PEGylated peptidic erythropoiesis-stimulating agent, in rodents.

http://www.wikidata.org/entity/Q37154338

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Erythropoietic stimulating agents.Non-erythropoietic tissue-protective peptides derived from erythropoietin: WO2009094172.Hematide™ for the treatment of chronic kidney disease-related anemia.Peginesatide for the treatment of renal disease-induced anemia.Absorption, distribution, metabolism and excretion of peginesatide, a novel erythropoiesis-stimulating agent, in rats Bone marrow-targeted liposomal carriers: a feasibility study in nonhuman primates.A subchronic murine intravenous pharmacokinetic and toxicity study of Hematide™, a PEGylated peptidic erythropoiesis-stimulating agent.Genotoxic assessment and toxicity evaluation of peginesatide in CByB6F1 hybrid mice.Erythropoiesis equivalence, pharmacokinetics and immune response following repeat hematide administration in cynomolgus monkeys.

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Chronic pharmacological and safety evaluation of Hematide, a PEGylated peptidic erythropoiesis-stimulating agent, in rodents.

http://www.wikidata.org/entity/Q37154338

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

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scientific article published on 16 December 2008

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Chronic pharmacological and sa ...... stimulating agent, in rodents.

@en

Chronic pharmacological and sa ...... stimulating agent, in rodents.

@nl

type

label

Chronic pharmacological and sa ...... stimulating agent, in rodents.

@en

Chronic pharmacological and sa ...... stimulating agent, in rodents.

@nl

prefLabel

Chronic pharmacological and sa ...... stimulating agent, in rodents.

@en

Chronic pharmacological and sa ...... stimulating agent, in rodents.

@nl

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J.1742-7843.2008.00347.X

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Basic and Clinical Pharmacology and Toxicology

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Chronic pharmacological and sa ...... -stimulating agent, in rodents

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Charles B Spainhour

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Daniel Norton

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Kei-Lai Fong

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Peter J Schatz

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Susan D Wilson

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Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates.

The effect of recombinant human erythropoietin on platelet counts is strongly modulated by the adequacy of iron supply.

Erythropoietin and platelet production.

Evaluation of the safety and pharmacodynamics of Hematide, a novel erythropoietic agent, in a phase 1, double-blind, placebo-controlled, dose-escalation study in healthy volunteers.

Pathology and pathophysiology of drug-induced arterial injury in laboratory animals and its implications on the evaluation of novel chemical entities for human clinical trials.

New agents that stimulate erythropoiesis.

The anemia of chronic renal failure: pathophysiology and effects of recombinant erythropoietin.

Preclinical evaluation of Hematide, a novel erythropoiesis stimulating agent, for the treatment of anemia.

Hematide is immunologically distinct from erythropoietin and corrects anemia induced by antierythropoietin antibodies in a rat pure red cell aplasia model.

Anemia: not just an innocent bystander?

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155-163

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scholarly article

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10.1111/J.1742-7843.2008.00347.X

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2

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Kathryn Woodburn

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2008-12-16T00:00:00Z

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19143750

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