Werner syndrome helicase has a critical role in DNA damage responses in the absence of a functional fanconi anemia pathway.
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Getting Ready for the Dance: FANCJ Irons Out DNA WrinklesDNA double-strand break repair pathway choice and cancerInteractive Roles of DNA Helicases and Translocases with the Single-Stranded DNA Binding Protein RPA in Nucleic Acid Metabolism.Molecular and cellular functions of the FANCJ DNA helicase defective in cancer and in Fanconi anemiaTargeting the homologous recombination pathway by small molecule modulatorsProtein degradation pathways regulate the functions of helicases in the DNA damage response and maintenance of genomic stabilityHuman RecQ helicases in DNA repair, recombination, and replication.CDK1 phosphorylates WRN at collapsed replication forks.Targeting an Achilles' heel of cancer with a WRN helicase inhibitorHelicases, G4-DNAs, and drug design.Biochemical and cell biological assays to identify and characterize DNA helicase inhibitors.Application of the microfluidic-assisted replication track analysis to measure DNA repair in human and mouse cellsHypoxia tolerance, longevity and cancer-resistance in the mole rat Spalax - a liver transcriptomics approach.BRIP1 overexpression is correlated with clinical features and survival outcome of luminal breast cancer subtypes.Small-Molecule Inhibitors Targeting DNA Repair and DNA Repair Deficiency in Research and Cancer Therapy.The Human Replicative Helicase, the CMG Complex, as a Target for Anti-cancer Therapy.Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks.New Insights Into DNA Helicases as Druggable Targets for Cancer Therapy
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Werner syndrome helicase has a critical role in DNA damage responses in the absence of a functional fanconi anemia pathway.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 July 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Werner syndrome helicase has a ...... tional fanconi anemia pathway.
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Werner syndrome helicase has a ...... tional fanconi anemia pathway.
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Werner syndrome helicase has a ...... tional fanconi anemia pathway.
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Werner syndrome helicase has a ...... tional fanconi anemia pathway.
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Werner syndrome helicase has a ...... tional fanconi anemia pathway.
@en
Werner syndrome helicase has a ...... tional fanconi anemia pathway.
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Werner syndrome helicase has a ...... tional fanconi anemia pathway.
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Chiara Iannascoli
Joshua A Sommers
Monika Aggarwal
Robert H Shoemaker
Robert M Brosh
Taraswi Banerjee
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P304
P356
10.1158/0008-5472.CAN-12-2975
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P577
2013-07-18T00:00:00Z