Signatures of purifying and local positive selection in human miRNAs
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Recent human adaptation: genomic approaches, interpretation and insightsMicroRNA polymorphisms and environmental smoke exposure as risk factors for oesophageal squamous cell carcinomaAnalysis of genomic variation in non-coding elements using population-scale sequencing data from the 1000 Genomes ProjectNatural Selection and Functional Potentials of Human Noncoding Elements Revealed by Analysis of Next Generation Sequencing DataSystematic analysis of microRNA targeting impacted by small insertions and deletions in human genome.A genomic portrait of the genetic architecture and regulatory impact of microRNA expression in response to infection.Exploration of signals of positive selection derived from genotype-based human genome scans using re-sequencing data.Global population-specific variation in miRNA associated with cancer risk and clinical biomarkersGenetic variation in microRNA networks: the implications for cancer research.Evidence for positive selection on a number of MicroRNA regulatory interactions during recent human evolutionrs4919510 in hsa-mir-608 is associated with outcome but not risk of colorectal cancerDesign and evaluation of a panel of single-nucleotide polymorphisms in microRNA genomic regions for association studies in human disease.MicroRNA-1 in Cardiac Diseases and CancersThe miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis.Microevolution of nematode miRNAs reveals diverse modes of selection.Polymorphisms in CTNNBL1 in relation to colorectal cancer with evolutionary implicationsFunctional Implications of Human-Specific Changes in Great Ape microRNAs.Differences in molecular evolutionary rates among microRNAs in the human and chimpanzee genomesBig effects of small RNAs: a review of microRNAs in anxietyGenetic interplay between HLA-C and MIR148A in HIV control and Crohn disease.Pleiotropic constraints, expression level, and the evolution of miRNA sequences.MiR-222 in Cardiovascular Diseases: Physiology and PathologyThe landscape of extreme genomic variation in the highly adaptable Atlantic killifish.Species-specific microRNA regulation influences phenotypic variability: perspectives on species-specific microRNA regulation.Omics technologies and the study of human ageing.MicroRNA sequence variation potentially contributes to within-species functional divergence in the nematode Caenorhabditis briggsae.Prioritization of genetic variants in the microRNA regulome as functional candidates in genome-wide association studies.Aberrant expression of miR-203 and its clinical significance in gastric and colorectal cancers.Contrasting signals of positive selection in genes involved in human skin-color variation from tests based on SNP scans and resequencing.Adaptive evolution and functional innovation of Populus-specific recently evolved microRNAs.Comprehensive analysis of the impact of SNPs and CNVs on human microRNAs and their regulatory genesIdentification of a dinucleotide signature that discriminates coding from non-coding long RNAs.Short intron-derived ncRNAsEvolution of the TIR domain-containing adaptors in humans: swinging between constraint and adaptation.Global investigation of the co-evolution of MIRNA genes and microRNA targets during soybean domestication.Emergence of New sRNAs in Enteric Bacteria is Associated with Low Expression and Rapid Evolution.MicroRNA Genetic Variation: From Population Analysis to Functional Implications of Three Allele Variants Associated with Cancer.Sequence Analysis of APOA5 Among the Kuwaiti Population Identifies Association of rs2072560, rs2266788, and rs662799 With TG and VLDL Levels.Comparing miRNA structure of mirtrons and non-mirtrons.Strong conservation of inbred mouse strain microRNA loci but broad variation in brain microRNAs due to RNA editing and isomiR expression.
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Signatures of purifying and local positive selection in human miRNAs
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 19 February 2009
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Signatures of purifying and local positive selection in human miRNAs
@en
Signatures of purifying and local positive selection in human miRNAs.
@nl
type
label
Signatures of purifying and local positive selection in human miRNAs
@en
Signatures of purifying and local positive selection in human miRNAs.
@nl
prefLabel
Signatures of purifying and local positive selection in human miRNAs
@en
Signatures of purifying and local positive selection in human miRNAs.
@nl
P2093
P2860
P50
P1476
Signatures of purifying and local positive selection in human miRNAs
@en
P2093
Christophe Antoniewski
Guillaume Laval
Hélène Quach
Judith R Kidd
Kenneth K Kidd
Michel Veuille
Nora Zidane
P2860
P304
P356
10.1016/J.AJHG.2009.01.022
P407
P577
2009-02-19T00:00:00Z