Functional genetic variation in the basal promoter of the organic cation/carnitine transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5).
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Pharmacogenomic discovery using cell-based modelsGenetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variationInstitutional Profile: The University of California Pharmacogenomics Center: at the interface of genomics, biological mechanisms and drug therapyThe pharmacogenomics of membrane transporters project: research at the interface of genomics and transporter pharmacology.Reduced renal clearance of cefotaxime in asians with a low-frequency polymorphism of OAT3 (SLC22A8)Functional characterization of liver enhancers that regulate drug-associated transporters.Pharmacogenomics of membrane transporters: past, present and futureDiscovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.Genetic and epigenetic regulation of the organic cation transporter 3, SLC22A3.Identification of OCTN2 variants and their association with phenotypes of Crohn's disease in a Korean population.Residual OCTN2 transporter activity, carnitine levels and symptoms correlate in patients with primary carnitine deficiency.Association study between OCTN1 functional haplotypes and Crohn's disease in a Korean population.Identification and Functional Characterization of Novel Genetic Variations in the OCTN1 Promoter.Genetic polymorphisms in placental transporters: implications for fetal drug exposure to oral antidiabetic agents.Significance of l-carnitine for human health.
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Functional genetic variation in the basal promoter of the organic cation/carnitine transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5).
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Functional genetic variation i ...... (SLC22A4) and OCTN2 (SLC22A5).
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Functional genetic variation i ...... n/carnitine transporters OCTN1
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type
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Functional genetic variation i ...... (SLC22A4) and OCTN2 (SLC22A5).
@en
Functional genetic variation i ...... n/carnitine transporters OCTN1
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Functional genetic variation i ...... (SLC22A4) and OCTN2 (SLC22A5).
@en
Functional genetic variation i ...... n/carnitine transporters OCTN1
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P2093
P2860
P356
P1476
Functional genetic variation i ...... (SLC22A4) and OCTN2 (SLC22A5).
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P2093
Doug Stryke
Harunobu Tahara
Kathleen M Giacomini
Michiko Kawamoto
Richard A Castro
Sook Wah Yee
Stephanie Hesselson
Susan J Johns
Thomas E Ferrin
Thomas J Urban
P2860
P304
P356
10.1124/JPET.108.146449
P407
P50
P577
2009-01-13T00:00:00Z