Stress-induced isoforms of MDM2 and MDM4 correlate with high-grade disease and an altered splicing network in pediatric rhabdomyosarcoma.
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The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA.Alternative splicing of MEF2C pre-mRNA controls its activity in normal myogenesis and promotes tumorigenicity in rhabdomyosarcoma cells.Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct waysSplicing factor SRSF1 negatively regulates alternative splicing of MDM2 under damage.Alternative splicing of spleen tyrosine kinase differentially regulates colorectal cancer progression.Aberrant splicing of the DMP1-ARF-MDM2-p53 pathway in cancerCancer subclonal genetic architecture as a key to personalized medicine.Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy.A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo.The Role of MDM2 in Promoting Genome Stability versus Instability.The Roles of MDM2 and MDMX in Cancer.
P2860
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P2860
Stress-induced isoforms of MDM2 and MDM4 correlate with high-grade disease and an altered splicing network in pediatric rhabdomyosarcoma.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Stress-induced isoforms of MDM ...... in pediatric rhabdomyosarcoma.
@en
Stress-induced isoforms of MDM ...... in pediatric rhabdomyosarcoma.
@nl
type
label
Stress-induced isoforms of MDM ...... in pediatric rhabdomyosarcoma.
@en
Stress-induced isoforms of MDM ...... in pediatric rhabdomyosarcoma.
@nl
prefLabel
Stress-induced isoforms of MDM ...... in pediatric rhabdomyosarcoma.
@en
Stress-induced isoforms of MDM ...... in pediatric rhabdomyosarcoma.
@nl
P2093
P2860
P356
P1433
P1476
Stress-induced isoforms of MDM ...... in pediatric rhabdomyosarcoma.
@en
P2093
Aishwarya G Jacob
Cheryl Bolinger
Daniel F Comiskey
Dawn S Chandler
Dennis O'Brien
Donald A Barkauskas
Fuad Mohammad
James R Anderson
Jordan T Gladman
Maria C Widmann
P2860
P304
P356
10.1593/NEO.13286
P577
2013-09-01T00:00:00Z