Differential regulation of sphingosine kinases 1 and 2 in lung injury.
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Sphingosine kinase 1 deficiency exacerbates LPS-induced neuroinflammationMouse Sphingosine Kinase 1a Is Negatively Regulated through Conventional PKC-Dependent Phosphorylation at S373 ResidueSphingosine Kinase 2 Deficiency Attenuates Kidney Fibrosis via IFN-γ.Interleukin-11 protects against renal ischemia and reperfusion injury.Sphingosine kinase-1 (SphK-1) regulates Mycobacterium smegmatis infection in macrophagesRole of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis.A novel function of sphingosine kinase 1 suppression of JNK activity in preventing inflammation and injury.Prolonged exposure to sphingosine 1-phosphate receptor-1 agonists exacerbates vascular leak, fibrosis, and mortality after lung injury.Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs.Inhibition of sphingosine 1-phosphate receptor 2 protects against renal ischemia-reperfusion injury.Update on acute lung injury and critical care medicine 2009.Sphingomyelin synthase 2 (SMS2) deficiency attenuates LPS-induced lung injuryPotential Link between the Sphingosine-1-Phosphate (S1P) System and Defective Alveolar Macrophage Phagocytic Function in Chronic Obstructive Pulmonary Disease (COPD).Glucocorticoids limit acute lung inflammation in concert with inflammatory stimuli by induction of SphK1.Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia.A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injuryTransient receptor potential channel 1 maintains adherens junction plasticity by suppressing sphingosine kinase 1 expression to induce endothelial hyperpermeability.Sphingosine 1-phosphate (S1P) receptors 1 and 2 coordinately induce mesenchymal cell migration through S1P activation of complementary kinase pathwaysSphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.N,N-dimethylacetamide regulates the proinflammatory response associated with endotoxin and prevents preterm birth.Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteinsSphingosine kinases are not required for inflammatory responses in macrophagesBiglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants.Sphingosine-1-phosphate: a potential therapeutic target for rheumatoid arthritis.Pharmacological targets in the renal peritubular microenvironment: implications for therapy for sepsis-induced acute kidney injury.Sphingosine-1-phosphate signaling in physiology and diseases.Sphingolipid regulation of tissue fibrosisOncogenic properties of sphingosine kinases in haematological malignancies.Dynamics of pulmonary endothelial barrier function in acute inflammation: mechanisms and therapeutic perspectives.Protection of LPS-induced murine acute lung injury by sphingosine-1-phosphate lyase suppression.Sepsis-Associated Encephalopathy: The Blood-Brain Barrier and the Sphingolipid Rheostat.Targeting sphingosine-1-phosphate signaling in lung diseases.Epigenetic regulation of pro-inflammatory cytokine secretion by sphingosine 1-phosphate (S1P) in acute lung injury: Role of S1P lyase.Thromboxane A2 exacerbates acute lung injury via promoting edema formation.SphK1 regulates proinflammatory responses associated with endotoxin and polymicrobial sepsis.Sphingolipids in Ventilator Induced Lung Injury: Role of Sphingosine-1-Phosphate Lyase.An Improved Isoform-Selective Assay for Sphingosine Kinase 1 Activity.Role of sphingomyelin synthesis in pulmonary endothelial cell cytoskeletal activation and endotoxin-induced lung injury.
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Differential regulation of sphingosine kinases 1 and 2 in lung injury.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Differential regulation of sphingosine kinases 1 and 2 in lung injury.
@en
Differential regulation of sphingosine kinases 1 and 2 in lung injury.
@nl
type
label
Differential regulation of sphingosine kinases 1 and 2 in lung injury.
@en
Differential regulation of sphingosine kinases 1 and 2 in lung injury.
@nl
prefLabel
Differential regulation of sphingosine kinases 1 and 2 in lung injury.
@en
Differential regulation of sphingosine kinases 1 and 2 in lung injury.
@nl
P2093
P2860
P1476
Differential regulation of sphingosine kinases 1 and 2 in lung injury.
@en
P2093
Carol Romano
Joe G N Garcia
Natalia Grinkina
Raj Wadgaonkar
Saad Sammani
Vipul Patel
Viswanathan Natarajan
Yutong Zhao
P2860
P304
P356
10.1152/AJPLUNG.90357.2008
P577
2009-01-23T00:00:00Z