Toward accurate reconstruction of functional protein networks
about
Met kinetic signature derived from the response to HGF/SF in a cellular model predicts breast cancer patient survivalPathway connectivity and signaling coordination in the yeast stress-activated signaling network.Large-scale elucidation of drug response pathways in humansA physarum-inspired prize-collecting steiner tree approach to identify subnetworks for drug repositioningLarge-scale models of signal propagation in human cells derived from discovery phosphoproteomic data.Integrating Transcriptomic and Proteomic Data Using Predictive Regulatory Network Models of Host Response to Pathogens.Integrating proteomic, transcriptional, and interactome data reveals hidden components of signaling and regulatory networks.Variants in exons and in transcription factors affect gene expression in trans.ResponseNet: revealing signaling and regulatory networks linking genetic and transcriptomic screening data.MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screeningPathways on demand: automated reconstruction of human signaling networksCluster-based assessment of protein-protein interaction confidenceLinking signaling pathways to transcriptional programs in breast cancer.Finding undetected protein associations in cell signaling by belief propagation.Adding protein context to the human protein-protein interaction network to reveal meaningful interactions.Discovering pathways by orienting edges in protein interaction networksModular analysis of the probabilistic genetic interaction networkSteiner tree methods for optimal sub-network identification: an empirical study.Structure-based systems biology for analyzing off-target bindingEnvironmental stresses disrupt telomere length homeostasis.Inferring host gene subnetworks involved in viral replication.Exploring in vivo cholesterol-mediated interactions between activated EGF receptors in plasma membrane with single-molecule optical tracking.Reconstruction and signal propagation analysis of the Syk signaling network in breast cancer cells.Linking the signaling cascades and dynamic regulatory networks controlling stress responses.Top-down network analysis to drive bottom-up modeling of physiological processesA context-sensitive framework for the analysis of human signalling pathways in molecular interaction networks.Swimming upstream: identifying proteomic signals that drive transcriptional changes using the interactome and multiple "-omics" datasetsNature vs nurture: interplay between the genetic control of telomere length and environmental factors.TOR links starvation responses to telomere length maintenance.Network-based drug repositioning.Biology of telomeres: lessons from budding yeast.Role of the ESCRT Complexes in Telomere BiologyGenome-wide studies of telomere biology in budding yeastA network-based analysis of colon cancer splicing changes reveals a tumorigenesis-favoring regulatory pathway emanating from ELK1Telomere length kinetics assay (TELKA) sorts the telomere length maintenance (tlm) mutants into functional groups.Reconstructing Boolean models of signaling.Long Telomeres Do Not Affect Cellular Fitness in Yeast.Energetic modeling and single-molecule verification of dynamic regulation on receptor complexes by actin corrals and lipid raft domains.Experimental design schemes for learning Boolean network models.The PathLinker app: Connect the dots in protein interaction networks.
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Toward accurate reconstruction of functional protein networks
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 March 2009
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Toward accurate reconstruction of functional protein networks
@en
Toward accurate reconstruction of functional protein networks.
@nl
type
label
Toward accurate reconstruction of functional protein networks
@en
Toward accurate reconstruction of functional protein networks.
@nl
prefLabel
Toward accurate reconstruction of functional protein networks
@en
Toward accurate reconstruction of functional protein networks.
@nl
P2093
P2860
P356
P1476
Toward accurate reconstruction of functional protein networks
@en
P2093
Adi Kimchi
Einat Zalckvar
Lior Ungar
Martin Kupiec
P2860
P356
10.1038/MSB.2009.3
P577
2009-03-17T00:00:00Z