HLA class II transgenic mice mimic human inflammatory diseases.
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Selected Aspects in the Pathogenesis of Autoimmune DiseasesAffinity maturation of human CD4 by yeast surface display and crystal structure of a CD4-HLA-DR1 complexDifferential responses to Smith D autoantigen by mice with HLA-DR and HLA-DQ transgenes: dominant responses by HLA-DR3 transgenic mice with diversification of autoantibodies to small nuclear ribonucleoprotein, double-stranded DNA, and nuclear antigePolyfunctional CD4+ T cell responses to a set of pathogenic arenaviruses provide broad population coverageHLA-DRB1-DQB1 haplotypes confer susceptibility and resistance to multiple sclerosis in Sardinia.The ethics of using transgenic non-human primates to study what makes us human.Rodent preclinical models for developing novel antiarthritic molecules: comparative biology and preferred methods for evaluating efficacy.Absence of IFN-γ increases brain pathology in experimental autoimmune encephalomyelitis-susceptible DRB1*0301.DQ8 HLA transgenic mice through secretion of proinflammatory cytokine IL-17 and induction of pathogenic monocytes/microglia into the centraReconstitution of huPBL-NSG mice with donor-matched dendritic cells enables antigen-specific T-cell activation.To B or not to B: role of B cells in pathogenesis of arthritis in HLA transgenic mice.Efficacy of HLA-DRB1∗03:01 and H2E transgenic mouse strains to correlate pathogenic thyroglobulin epitopes for autoimmune thyroiditis.Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery.Superantigens produced by catheter-associated Staphylococcus aureus elicit systemic inflammatory disease in the absence of bacteremia.Influence of asthma epidemiology on the risk for other diseases.Complicating autoimmune diseases in myasthenia gravis: a review.HLA class II molecules influence susceptibility versus protection in inflammatory diseases by determining the cytokine profileSpontaneous autoimmune myocarditis and cardiomyopathy in HLA-DQ8.NODAbo transgenic mice.Two discreet subsets of CD8 T cells modulate PLP(91-110) induced experimental autoimmune encephalomyelitis in HLA-DR3 transgenic mice.Effective Arrestin-Specific Immunotherapy of Experimental Autoimmune Uveitis with RTL: A Prospect for Treatment of Human Uveitis.HLA-DQ8 (DQB1*0302)-restricted Th17 cells exacerbate experimental autoimmune encephalomyelitis in HLA-DR3-transgenic mice.Myelin-reactive type B T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic miceHLA class II (DR0401) molecules induce Foxp3+ regulatory T cell suppression of B cells in Plasmodium yoelii strain 17XNL malariaRole of HLA class II genes in susceptibility and resistance to multiple sclerosis: studies using HLA transgenic miceA retrospective review of 15 patients with familial myasthenia gravis over a period of 25 years.Animal Models Used to Study Superantigen-Mediated Diseases.Direct interaction of natural and synthetic catechins with signal transducer activator of transcription 1 affects both its phosphorylation and activity.HLA-DR alleles determine responsiveness to Borrelia burgdorferi antigens in a mouse model of self-perpetuating arthritisHLA-DR polymorphisms influence in vivo responses to staphylococcal toxic shock syndrome toxin-1 in a transgenic mouse model.HLA-DR7 and HLA-DQ2: Transgenic mouse strains tested as a model system for ximelagatran hepatotoxicityLimitations of Current in Vivo Mouse Models for the Study of Chikungunya Virus Pathogenesis.Scientific Opinion on the assessment of allergenicity of GM plants and microorganisms and derived food and feedSuppressed oligodendrocyte steroidogenesis in multiple sclerosis: Implications for regulation of neuroinflammation.Concomitant Disruption of CD4 and CD8 Genes Facilitates the Development of Double Negative αβ TCR+ Peripheral T Cells That Respond Robustly to Staphylococcal Superantigen.Influence of HLA-DR polymorphism and allergic sensitization on humoral immune responses to intact pneumococcus in a transgenic mouse model.Human Gut-Derived Commensal Bacteria Suppress CNS Inflammatory and Demyelinating Disease.
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P2860
HLA class II transgenic mice mimic human inflammatory diseases.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on January 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
HLA class II transgenic mice mimic human inflammatory diseases.
@en
HLA class II transgenic mice mimic human inflammatory diseases.
@nl
type
label
HLA class II transgenic mice mimic human inflammatory diseases.
@en
HLA class II transgenic mice mimic human inflammatory diseases.
@nl
prefLabel
HLA class II transgenic mice mimic human inflammatory diseases.
@en
HLA class II transgenic mice mimic human inflammatory diseases.
@nl
P1476
HLA class II transgenic mice mimic human inflammatory diseases
@en
P2093
Chella S David
Govindarajan Rajagopalan
P304
P356
10.1016/S0065-2776(08)00002-3
P577
2008-01-01T00:00:00Z